UBXN11 Antibody (PACO13060)
- SKU:
- PACO13060
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | UBXN11 Antibody (PACO13060) |
| Antibody SKU: | PACO13060 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC |
| Recommended Dilutions: | |
| Species Reactivity: | Human, Mouse, Rat |
| Immunogen: | Human UBXN11 |
| Form: | Liquid |
| Storage Buffer: | PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
| Purification Method: | Antigen Affinity Purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Synonyms: | UBX domain protein 11;UBXN11;COA-1;DKFZp686F04228;PP2243;SOC;SOCI;UBXD5 ; |
| UniProt Protein Function: | UBXN11: May be involved in the reorganization of actin cytoskeleton mediated by RND1, RND2 AND RND3. Promotes RHOA activation mediated by GNA12 and GNA13. 8 isoforms of the human protein are produced by alternative splicing.Protein type: CytoskeletalChromosomal Location of Human Ortholog: 1p36.11Cellular Component: cytoplasm; cytoskeletonMolecular Function: protein binding; ubiquitin bindingBiological Process: proteasomal ubiquitin-dependent protein catabolic process |
| UniProt Protein Details: | |
| NCBI Summary: | This gene encodes a protein with a divergent C-terminal UBX domain. The homologous protein in the rat interacts with members of the Rnd subfamily of Rho GTPases at the cell periphery through its C-terminal region. It also interacts with several heterotrimeric G proteins through their G-alpha subunits and promotes Rho GTPase activation. It is proposed to serve a bidirectional role in the promotion and inhibition of Rho activity through upstream signaling pathways. The 3' coding sequence of this gene contains a polymoprhic region of 24 nt tandem repeats. Several transcripts containing between 1.5 and five repeat units have been reported. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q5T124 |
| NCBI GenInfo Identifier: | 146325810 |
| NCBI Gene ID: | 91544 |
| NCBI Accession: | Q5T124.2 |
| UniProt Secondary Accession: | Q5T124,Q5T117, Q5T120, Q5T125, Q5T126, Q5T129, Q5T131 Q5T133, Q63HM6, Q71RB3 |
| UniProt Related Accession: | Q5T124 |
| Molecular Weight: | 49,445 Da |
| NCBI Full Name: | UBX domain-containing protein 11 |
| NCBI Synonym Full Names: | UBX domain protein 11 |
| NCBI Official Symbol: | UBXN11 |
| NCBI Official Synonym Symbols: | SOC; SOCI; COA-1; UBXD5; PP2243 |
| NCBI Protein Information: | UBX domain-containing protein 11 |
| UniProt Protein Name: | UBX domain-containing protein 11 |
| UniProt Synonym Protein Names: | Colorectal tumor-associated antigen COA-1; Socius; UBX domain-containing protein 5 |
| Protein Family: | UBX domain-containing protein |
| UniProt Gene Name: | UBXN11 |
| UniProt Entry Name: | UBX11_HUMAN |
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