UBXN1 Antibody (PACO13059)
- SKU:
- PACO13059
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | UBXN1 Antibody (PACO13059) |
| Antibody SKU: | PACO13059 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | |
| Species Reactivity: | Human, Mouse, Rat |
| Immunogen: | Human UBXN1 |
| Form: | Liquid |
| Storage Buffer: | PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
| Purification Method: | Antigen Affinity purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Synonyms: | UBX domain protein 1;UBXN1;2B28;UBXD10 ; |
| UniProt Protein Function: | UBXN1: Ubiquitin-binding protein that interacts with the BRCA1- BARD1 heterodimer, and regulates its activity. Specifically binds 'Lys-6'-linked polyubiquitin chains. Interaction with autoubiquitinated BRCA1, leads to inhibit the E3 ubiquitin-protein ligase activity of the BRCA1-BARD1 heterodimer. Component of a complex required to couple deglycosylation and proteasome-mediated degradation of misfolded proteins in the endoplasmic reticulum that are retrotranslocated in the cytosol. 2 isoforms of the human protein are produced by alternative splicing.Protein type: Adaptor/scaffold; Ubiquitin conjugating system; Proteasome complexChromosomal Location of Human Ortholog: 11q12.3Cellular Component: proteasome complex; cell soma; cytoplasm; dendrite; nucleusMolecular Function: ubiquitin binding; protein binding; ubiquitin protein ligase binding; polyubiquitin binding; ATPase bindingBiological Process: proteasomal ubiquitin-dependent protein catabolic process; negative regulation of protein ubiquitination; negative regulation of proteasomal ubiquitin-dependent protein catabolic process |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q04323 |
| NCBI GenInfo Identifier: | 12655045 |
| NCBI Gene ID: | 51035 |
| NCBI Accession: | AAH01372.1 |
| UniProt Secondary Accession: | Q04323,Q9BV93, Q9BVV5 |
| UniProt Related Accession: | Q04323 |
| Molecular Weight: | 35,107 Da |
| NCBI Full Name: | UBX domain protein 1 |
| NCBI Synonym Full Names: | UBX domain protein 1 |
| NCBI Official Symbol: | UBXN1 |
| NCBI Official Synonym Symbols: | 2B28; SAKS1; UBXD10 |
| NCBI Protein Information: | UBX domain-containing protein 1; SAPK substrate protein 1; UBA/UBX 33.3 kDa protein |
| UniProt Protein Name: | UBX domain-containing protein 1 |
| UniProt Synonym Protein Names: | SAPK substrate protein 1; UBA/UBX 33.3 kDa protein |
| Protein Family: | |
| UniProt Gene Name: | UBXN1 |
| UniProt Entry Name: | UBXN1_HUMAN |
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