UBTD2 Antibody (PACO20810)
- SKU:
- PACO20810
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | UBTD2 Antibody (PACO20810) |
| Antibody SKU: | PACO20810 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:30-1:150 |
| Species Reactivity: | Human, Mouse |
| Immunogen: | Synthetic peptide of human UBTD2 |
| Form: | Liquid |
| Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Purification Method: | Antigen affinity purification |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using PACO20810(UBTD2 Antibody) at dilution 1/35, on the right is treated with synthetic peptide. (Original magnification: x200). |
 | The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using PACO20810(UBTD2 Antibody) at dilution 1/35, on the right is treated with synthetic peptide. (Original magnification: x200). |
| Background: | UBTD2 (ubiquitin domain containing 2), also known as DCUBP (dendritic cell-derived ubiquitin-like protein), DC-UbP or SB72, is a 234 amino acid, cytoplasmic and mitochondrial ubiquitin-like (UbL) protein that contains one C-terminal UbL domain. UbL proteins are involved in a variety of cellular processes, including DNA repair, protein sorting, apoptosis, protein degradation, cell division and autophagy. Predominantly expressed in dendritic cells and detected at high levels in tumor cell lines, UBTD2 has been implicated in apoptosis, cellular differentiation and tumorigenesis. The UbL domain of UBTD2 is 55% similar and 28.6% identical to the amino acid, sequence of ubiquitin, but it lacks the Gly-Gly motif that is essential for ubiquitination. As its UbL domain does not actively ubiquitinate proteins, UBTD2 is believed to function as a shuttle factor involved in the ubiquitin system. |
| Synonyms: | ubiquitin domain containing 2 |
| UniProt Protein Function: | UBTD2: Chromosomal Location of Human Ortholog: 5q35.1Cellular Component: cytoplasmMolecular Function: ubiquitin binding |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q8WUN7 |
| NCBI GenInfo Identifier: | 109896149 |
| NCBI Gene ID: | 92181 |
| NCBI Accession: | Q8WUN7.2 |
| UniProt Secondary Accession: | Q8WUN7,Q8TDQ3 |
| UniProt Related Accession: | Q8WUN7 |
| Molecular Weight: | 26,190 Da |
| NCBI Full Name: | Ubiquitin domain-containing protein 2 |
| NCBI Synonym Full Names: | ubiquitin domain containing 2 |
| NCBI Official Symbol: | UBTD2 |
| NCBI Official Synonym Symbols: | DCUBP |
| NCBI Protein Information: | ubiquitin domain-containing protein 2 |
| UniProt Protein Name: | Ubiquitin domain-containing protein 2 |
| UniProt Synonym Protein Names: | Dendritic cell-derived ubiquitin-like protein; DC-UbP; Ubiquitin-like protein SB72 |
| Protein Family: | Ubiquitin domain-containing protein |
| UniProt Gene Name: | UBTD2 |
| UniProt Entry Name: | UBTD2_HUMAN |
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