Description
Product Name: | UBE2L6 Monoclonal Antibody |
Product Code: | CAB23917 |
Reactivity: | Human, Mouse, Rat |
Applications: | Western blotting, Immunohistochemistry |
Host Species: | Rabbit |
Purification Method: | Affinity purification |
Isotype: | IgG |
Clone No: | ARC62291 |
Reactivity: | Human, Mouse, Rat |
Tested Applications: | WB, IHC-P, ELISA |
Key Applications: | Western blotting, Immunohistochemistry |
Recommended Dilution: | WB 1:1000-1:5000, IHC-P 1:50-1:200 |
Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
Positive Samples: | U-87MG, Mouse spleen, Rat liver |
Cellular Location: | Cytosol, nucleoplasm, nucleus |
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s) and ubiquitin-protein ligases (E3s). This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is highly similar in primary structure to the enzyme encoded by the UBE2L3 gene. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 54-153 of human UBE2L6 (NP_004214.1). |
Sequence: | RISFP PEYPF KPPMI KFTTK IYHPN VDENG QICLP IISSE NWKPC TKTCQ VLEAL NVLVN RPNIR EPLRM DLADL LTQNP ELFRK NAEEF TLRFG VDRPS |
Synonyms: | RIG-B, UBCH8 |
Calculated MW: | 18kDa |
Observed MW: | 18kDa |