UBE2C Monoclonal Antibody
- SKU:
- CAB24740
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
- Applications:
- IHC
Description
| Product Name: | UBE2C Monoclonal Antibody |
| Product Code: | CAB24740 |
| Reactivity: | Human, Mouse, Rat |
| Applications: | Western blotting, Immunohistochemistry |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC62956 |
| Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB, IHC-P, ELISA |
| Key Applications: | Western blotting, Immunohistochemistry |
| Recommended Dilution: | WB 1:1000-1:5000, IHC-P 1:50-1:200 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
| Positive Samples: | MCF7, HeLa, NIH/3T3, Rat thymus |
| Cellular Location: | Cytosol, Nucleoplasm, Nucleus, Plasma membrane |
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, ubiquitin-conjugating enzymes, and ubiquitin-protein ligases. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. The encoded protein is required for the destruction of mitotic cyclins and for cell cycle progression, and may be involved in cancer progression. Multiple transcript variants encoding different isoforms have been found for this gene. Pseudogenes of this gene have been defined on chromosomes 4, 14, 15, 18, and 19.
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-179 of human TLR4 (NP_008950.1). |
| Sequence: | MASQN RDPAA TSVAA ARKGA EPSGG AARGP VGKRL QQELM TLMMS GDKGI SAFPE SDNLF KWVGT IHGAA GTVYE DLRYK LSLEF PSGYP YNAPT VKFLT PCYHP NVDTQ GNICL DILKE KWSAL YDVRT ILLSI QSLLG EPNID SPLNT HAAEL WKNPT AFKKY LQETY SKQVT SQEP |
| Synonyms: | UBCH10, dJ447F3.2 |
| Calculated MW: | 20kDa |
| Observed MW: | 20kDa |
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