Description
Antibody Name: | UBE2A/UBE2B Antibody |
Antibody SKU: | PACO01799 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB |
Recommended Dilutions: | WB:1:500-1:2000 |
Species Reactivity: | Human, Mouse, Rat |
Immunogen: | synthesized peptide derived from the C-terminal region of human UBE2A/B. |
Form: | Liquid |
Storage Buffer: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Synonyms: | UBE2A; RAD6A; Ubiquitin-conjugating enzyme E2 A; RAD6 homolog A; HR6A; hHR6A; Ubiquitin carrier protein A; Ubiquitin-protein ligase A; UBE2B; RAD6B; Ubiquitin-conjugating enzyme E2 B; |
UniProt Protein Function: | UBE2A: a ubiquitin-protein ligase, a member of the ubiquitin-conjugating enzyme family. Homologous to the yeast DNA repair gene RAD6. Interacts with RAD18. Required for postreplication repair of UV-damaged DNA. |
UniProt Protein Details: | Protein type:EC 6.3.2.19; Ubiquitin conjugating system; Ubiquitin ligase; Ligase Chromosomal Location of Human Ortholog: Xq24 Cellular Component: XY body; cytoplasm; nuclear chromatin; chromatin; cytosol Molecular Function:protein binding; small conjugating protein ligase activity; ubiquitin protein ligase binding; ubiquitin-protein ligase activity; ATP binding; ligase activity Biological Process: ubiquitin-dependent protein catabolic process; proteasomal ubiquitin-dependent protein catabolic process; antigen processing and presentation of peptide antigen via MHC class I; protein autoubiquitination; protein polyubiquitination; maternal process involved in pregnancy; postreplication repair; in utero embryonic development; positive regulation of cell proliferation; DNA repair; histone H2A ubiquitination; response to UV Disease: Mental Retardation, X-linked, Syndromic, Nascimento Type |
UniProt Code: | P49459 |
NCBI GenInfo Identifier: | 33518639 |
NCBI Gene ID: | 7319 |
NCBI Accession: | P49459.2 |
Molecular Weight: | |
NCBI Full Name: | Ubiquitin-conjugating enzyme E2 A |
UniProt Protein Name: | Ubiquitin-conjugating enzyme E2 A |
UniProt Synonym Protein Names: | RAD6 homolog A; HR6A; hHR6A; Ubiquitin carrier protein A; Ubiquitin-protein ligase A |
Protein Family: | Ubiquitin-conjugating enzyme |
UniProt Gene Name: | UBE2A |
UniProt Entry Name: | UBE2A_HUMAN |