Description
| Antibody Name: | TYW1B Antibody (PACO13008) |
| Antibody SKU: | PACO13008 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC |
| Recommended Dilutions: | |
| Species Reactivity: | Human, Mouse, Rat |
| Immunogen: | Human TYW1B |
| Form: | Liquid |
| Storage Buffer: | PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
| Purification Method: | Antigen Affinity purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Synonyms: | tRNA-yW synthesizing protein 1 homolog B (non-protein coding);TYW1B;MGC87315;NCRNA00069;RSAFD2 ; |
| UniProt Protein Function: | TYW1B: Probable component of the wybutosine biosynthesis pathway. Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3'-position adjacent to the anticodon of eukaryotic phenylalanine tRNA. Belongs to the TYW1 family.Protein type: EC 4.1.3.44Chromosomal Location of Human Ortholog: 7q11.23Molecular Function: FMN binding; iron ion binding; 4 iron, 4 sulfur cluster binding; lyase activity; oxidoreductase activityBiological Process: tRNA processing |
| UniProt Protein Details: | |
| NCBI Summary: | Wybutosine (yW) is a hypermodified guanosine found in phenylalanine tRNA adjacent to the anticodon that stabilizes codon-anticodon interactions in the ribosome. In yeast, the homolog of this gene is essential for the synthesis of wybutosine. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015] |
| UniProt Code: | Q6NUM6 |
| NCBI GenInfo Identifier: | 50726981 |
| NCBI Gene ID: | 55253 |
| NCBI Accession: | NP_060734.2 |
| UniProt Secondary Accession: | Q6NUM6 |
| UniProt Related Accession: | Q6NUM6,Q9NV66 |
| Molecular Weight: | 34 kDa |
| NCBI Full Name: | |
| NCBI Synonym Full Names: | tRNA-yW synthesizing protein 1 homolog |
| NCBI Official Symbol: | TYW1 |
| NCBI Official Synonym Symbols: | TYW1A; RSAFD1; YPL207W |
| NCBI Protein Information: | S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase |
| UniProt Protein Name: | S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase |
| UniProt Synonym Protein Names: | Radical S-adenosyl methionine and flavodoxin domain-containing protein 2; tRNA wybutosine-synthesizing protein 1 homolog B |
| Protein Family: | |
| UniProt Gene Name: | TYW1B |
| UniProt Entry Name: | TYW1B_HUMAN |