TXNRD3 Antibody (PACO13006)
- SKU:
- PACO13006
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | TXNRD3 Antibody (PACO13006) |
| Antibody SKU: | PACO13006 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC |
| Recommended Dilutions: | |
| Species Reactivity: | Human |
| Immunogen: | Human TXNRD3 |
| Form: | Liquid |
| Storage Buffer: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
| Purification Method: | Antigen Affinity purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Synonyms: | thioredoxin reductase 3;TXNRD3;TGR;TR2;TRXR3 ; |
| UniProt Protein Function: | TXNRD3: Displays thioredoxin reductase, glutaredoxin and glutathione reductase activities. Catalyzes disulfide bond isomerization. Promotes disulfide bond formation between GPX4 and various sperm proteins and may play a role in sperm maturation by promoting formation of sperm structural components. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.Protein type: EC 1.8.1.9; OxidoreductaseChromosomal Location of Human Ortholog: 3q21.3 |
| UniProt Protein Details: | |
| NCBI Summary: | This gene encodes a member of the family of pyridine nucleotide oxidoreductases. This protein catalyzes the reduction of thioredoxin, and is implicated in the defense against oxidative stress. It contains a selenocysteine (Sec) residue (which is essential for catalytic activity), encoded by a UGA codon, at the penultimate C-terminal position. The 3' UTR of Sec-containing genes have a common stem-loop structure, the sec insertion sequence (SECIS), which is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010] |
| UniProt Code: | Q86VQ6 |
| NCBI GenInfo Identifier: | 510120859 |
| NCBI Gene ID: | 114112 |
| NCBI Accession: | Q86VQ6.4 |
| UniProt Secondary Accession: | Q86VQ6,Q6PIS8, Q9NNW6, Q9P101 |
| UniProt Related Accession: | Q86VQ6 |
| Molecular Weight: | 70,683 Da |
| NCBI Full Name: | Thioredoxin reductase 3 |
| NCBI Synonym Full Names: | thioredoxin reductase 3 |
| NCBI Official Symbol: | TXNRD3 |
| NCBI Official Synonym Symbols: | TGR; TR2; TRXR3 |
| NCBI Protein Information: | thioredoxin reductase 3 |
| UniProt Protein Name: | Thioredoxin reductase 3 |
| UniProt Synonym Protein Names: | Thioredoxin and glutathione reductase; Thioredoxin reductase TR2 |
| Protein Family: | Thioredoxin reductase |
| UniProt Gene Name: | TXNRD3 |
| UniProt Entry Name: | TRXR3_HUMAN |
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