TXNIP Polyclonal Antibody
- SKU:
- CAB24289
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Description
| Product Name: | TXNIP Polyclonal Antibody |
| Product Code: | CAB24289 |
| Reactivity: | Mouse, Rat |
| Applications: | Western blotting |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Reactivity: | Mouse, Rat |
| Tested Applications: | WB, ELISA |
| Key Applications: | Western blotting |
| Recommended Dilution: | WB 1:1000-1:5000 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 50% glycerol, pH7.3. |
| Positive Samples: | Mouse thymus |
| Cellular Location: | Cytoplasm |
This gene encodes a thioredoxin-binding protein that is a member of the alpha arrestin protein family. Thioredoxin is a thiol-oxidoreductase that is a major regulator of cellular redox signaling which protects cells from oxidative stress. This protein inhibits the antioxidative function of thioredoxin resulting in the accumulation of reactive oxygen species and cellular stress. This protein also functions as a regulator of cellular metabolism and of endoplasmic reticulum (ER) stress. This protein may also function as a tumor suppressor. Alternate splicing results in multiple transcript variants.
| Immunogen: | A synthetic peptide corresponding to a sequence within human TXNIP. |
| Sequence: | MVMFK KIKSF EVVFN DPEKV YGSGE KVAGR VIVEV CEVTR VKAVR ILACG VAKVL WMQGS QQCKQ TSEYL RYEDT LLLED QPTGE NEMVI MRPGN KYEYK |
| Synonyms: | THIF, VDUP1, ARRDC6, HHCPA78, EST01027 |
| Calculated MW: | 44kDa |
| Observed MW: | 55kDa |
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