TXNDC8 Antibody (PACO36390)
- SKU:
- PACO36390
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | TXNDC8 Antibody (PACO36390) |
| Antibody SKU: | PACO36390 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Thioredoxin domain-containing protein 8 protein (1-115AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Immunohistochemistry of paraffin-embedded human liver tissue using PACO36390 at dilution of 1:100. |
 | Immunohistochemistry of paraffin-embedded human brain tissue using PACO36390 at dilution of 1:100. |
| Background: | May be required for post-translational modifications of proteins required for acrosomal biogenesis. May act by reducing disulfide bonds within the sperm. |
| Synonyms: | Thioredoxin domain-containing protein 8 (Spermatid-specific thioredoxin-3) (Sptrx-3) (Thioredoxin-6), TXNDC8, SPTRX3 TRX6 |
| UniProt Protein Function: | TXNDC8: May be required for post-translational modifications of proteins required for acrosomal biogenesis. May act by reducing disulfide bonds within the sperm. Belongs to the thioredoxin family. 2 isoforms of the human protein are produced by alternative splicing.Chromosomal Location of Human Ortholog: 9q31.3Cellular Component: Golgi apparatus; cytoplasm; acrosomeMolecular Function: protein disulfide oxidoreductase activityBiological Process: acrosome formation; cell redox homeostasis; multicellular organismal development; spermatogenesis; glycerol ether metabolic process |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q6A555 |
| NCBI GenInfo Identifier: | 51510891 |
| NCBI Gene ID: | 255220 |
| NCBI Accession: | NP_001003936.1 |
| UniProt Secondary Accession: | Q6A555,Q5T934, A1L4I2, A6NDK7 |
| UniProt Related Accession: | Q6A555 |
| Molecular Weight: | 14,575 Da |
| NCBI Full Name: | thioredoxin domain-containing protein 8 isoform a |
| NCBI Synonym Full Names: | thioredoxin domain containing 8 (spermatozoa) |
| NCBI Official Symbol: | TXNDC8 |
| NCBI Official Synonym Symbols: | TRX6; SPTRX-3; bA427L11.2 |
| NCBI Protein Information: | thioredoxin domain-containing protein 8; thioredoxin 6; sperm-specific thioredoxin 3; spermatid-specific thioredoxin-3; spermatocyte/spermatid-specific thioredoxin-3 |
| UniProt Protein Name: | Thioredoxin domain-containing protein 8 |
| UniProt Synonym Protein Names: | Spermatid-specific thioredoxin-3; Sptrx-3; Thioredoxin-6 |
| Protein Family: | Thioredoxin domain-containing protein |
| UniProt Gene Name: | TXNDC8 |
| UniProt Entry Name: | TXND8_HUMAN |
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