TUT1 Antibody (PACO05061)
- SKU:
- PACO05061
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | TUT1 Antibody (PACO05061) |
| Antibody SKU: | PACO05061 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC |
| Recommended Dilutions: | ELISA:1:20000, WB:1:500-1:2000, IHC:1:100-1:300 |
| Species Reactivity: | Human |
| Immunogen: | Synthesized peptide derived from the Internal region of human TUTase. |
| Form: | Liquid |
| Storage Buffer: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Synonyms: | TUT1; RBM21; Speckle targeted PIP5K1A-regulated poly(A) polymerase; Star-PAP; RNA-binding motif protein 21; RNA-binding protein 21; U6 snRNA-specific terminal uridylyltransferase 1; U6-TUTase |
| UniProt Protein Function: | RBM21: Highly specific terminal uridylyltransferase that exclusively accepts U6 snRNA as substrate. U6 snRNA is unique in that nucleotides are both added to and removed from its 3'-end. U6-TUTase is responsible for a controlled elongation reaction that results in the restoration of the four 3'-terminal UMP-residues found in newly transcribed U6 snRNA. Does not play a role in replication-dependent histone mRNA degradation.Protein type: Nucleolus; EC 2.7.7.52; EC 2.7.7.19; TransferaseChromosomal Location of Human Ortholog: 11q12.2Cellular Component: nucleoplasm; intercellular bridge; nucleolus; nuclear speck; mRNA cleavage and polyadenylation specificity factor complexMolecular Function: polynucleotide adenylyltransferase activity; protein binding; enzyme binding; mRNA 3'-UTR binding; RNA binding; metal ion binding; RNA uridylyltransferase activity; ATP bindingBiological Process: snRNA processing; mRNA polyadenylation; mRNA cleavage |
| UniProt Protein Details: | |
| NCBI Summary: | This gene encodes a nucleotidyl transferase that functions as both a terminal uridylyltransferase and a nuclear poly(A) polymerase. The encoded enzyme specifically adds and removes nucleotides from the 3' end of small nuclear RNAs and select mRNAs and may function in controlling gene expression and cell proliferation.[provided by RefSeq, Apr 2009] |
| UniProt Code: | Q9H6E5 |
| NCBI GenInfo Identifier: | 226371750 |
| NCBI Gene ID: | 64852 |
| NCBI Accession: | NP_073741.2 |
| UniProt Secondary Accession: | Q9H6E5,Q2NL65, Q7L583, Q9H6H7, A1A527, A8K995 |
| UniProt Related Accession: | Q9H6E5 |
| Molecular Weight: | 95kd |
| NCBI Full Name: | speckle targeted PIP5K1A-regulated poly(A) polymerase |
| NCBI Synonym Full Names: | terminal uridylyl transferase 1, U6 snRNA-specific |
| NCBI Official Symbol: | TUT1 |
| NCBI Official Synonym Symbols: | PAPD2; RBM21; URLC6; TUTase; STARPAP |
| NCBI Protein Information: | speckle targeted PIP5K1A-regulated poly(A) polymerase |
| UniProt Protein Name: | Speckle targeted PIP5K1A-regulated poly(A) polymerase |
| UniProt Synonym Protein Names: | RNA-binding motif protein 21; RNA-binding protein 21; U6 snRNA-specific terminal uridylyltransferase 1 (EC:2.7.7.52); U6-TUTase |
| Protein Family: | Speckle targeted PIP5K1A-regulated poly(A) polymerase |
| UniProt Gene Name: | TUT1 |
| UniProt Entry Name: | STPAP_HUMAN |
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