TUBGCP4 Antibody (PACO55282)
- SKU:
- PACO55282
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Applications:
- IHC
- Applications:
- IF
- Applications:
- IP
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | TUBGCP4 Antibody (PACO55282) |
| Antibody SKU: | PACO55282 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC, IF, IP |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:5000, IHC:1:20-1:200, IF:1:200-1:500, IP:1:200-1:2000, |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Gamma-tubulin complex component 4 protein (203-309AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western Blot. Positive WB detected in: MCF-7 whole cell lysate. All lanes: TUBGCP4 antibody at 3µg/ml. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 77 kDa. Observed band size: 77 kDa. |
 | Immunohistochemistry of paraffin-embedded human testis tissue using PACO55282 at dilution of 1:100. |
 | Immunohistochemistry of paraffin-embedded human small intestine tissue using PACO55282 at dilution of 1:100. |
| Background: | Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome. |
| Synonyms: | Gamma-tubulin complex component 4 (GCP-4) (hGCP4) (Gamma-ring complex protein 76 kDa) (h76p) (hGrip76), TUBGCP4, 76P GCP4 |
| UniProt Protein Function: | Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome. |
| UniProt Protein Details: | |
| NCBI Summary: | This gene encodes a component of the gamma-tubulin ring complex, which is required for microtubule nucleation. In mammalian cells, the protein localizes to centrosomes in association with gamma-tubulin. Crystal structure analysis revealed a structure composed of five helical bundles arranged around conserved hydrophobic cores. An exposed surface area located in the C-terminal domain is essential and sufficient for direct binding to gamma-tubulin. Mutations in this gene that alter microtubule organization are associated with microcephaly and chorioretinopathy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2015] |
| UniProt Code: | Q9UGJ1 |
| NCBI GenInfo Identifier: | 556695399 |
| NCBI Gene ID: | 27229 |
| NCBI Accession: | NP_001273343.1 |
| UniProt Secondary Accession: | Q9UGJ1,Q969X3, Q9NVF0, B3KNK6 |
| UniProt Related Accession: | Q9UGJ1 |
| Molecular Weight: | 76,018 Da |
| NCBI Full Name: | gamma-tubulin complex component 4 isoform a |
| NCBI Synonym Full Names: | tubulin gamma complex associated protein 4 |
| NCBI Official Symbol: | TUBGCP4 |
| NCBI Official Synonym Symbols: | 76P; GCP4; GCP-4; Grip76; MCCRP3 |
| NCBI Protein Information: | gamma-tubulin complex component 4 |
| UniProt Protein Name: | Gamma-tubulin complex component 4 |
| UniProt Synonym Protein Names: | Gamma-ring complex protein 76 kDa; h76p; hGrip76 |
| Protein Family: | Gamma-tubulin complex component |
| UniProt Gene Name: | TUBGCP4 |
| UniProt Entry Name: |
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