TUBB2B Antibody (PACO12986)
- SKU:
- PACO12986
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | TUBB2B Antibody (PACO12986) |
| Antibody SKU: | PACO12986 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA |
| Recommended Dilutions: | |
| Species Reactivity: | Human, Mouse, Rat |
| Immunogen: | Human TUBB2B |
| Form: | Liquid |
| Storage Buffer: | PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.320°C, Avoid freeze / thaw cycles. |
| Purification Method: | Antigen Affinity Purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Synonyms: | 50kd; |
| UniProt Protein Function: | TUBB2B: Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha-chain. TUBB2B is implicated in neuronal migration. Defects in TUBB2B are a cause of polymicrogyria asymmetric (PMGA). PMGA is a malformation of the cortex in which the brain surface is irregular and characterized by an excessive number of small gyri with abnormal lamination. Belongs to the tubulin family. |
| UniProt Protein Details: | Protein type:Cytoskeletal Chromosomal Location of Human Ortholog: 6p25 Cellular Component: microtubule; nucleus Molecular Function:protein binding Biological Process: neuron migration Disease: Polymicrogyria, Symmetric Or Asymmetric |
| NCBI Summary: | The protein encoded by this gene is a beta isoform of tubulin, which binds GTP and is a major component of microtubules. This gene is highly similar to TUBB2A and TUBB2C. Defects in this gene are a cause of asymmetric polymicrogyria. [provided by RefSeq, Mar 2010] |
| UniProt Code: | Q9BVA1 |
| NCBI GenInfo Identifier: | 74761283 |
| NCBI Gene ID: | 347733 |
| NCBI Accession: | Q9BVA1.1 |
| UniProt Secondary Accession: | Q9BVA1,A8K068, |
| UniProt Related Accession: | Q9BVA1 |
| Molecular Weight: | 49,953 Da |
| NCBI Full Name: | Tubulin beta-2B chain |
| NCBI Synonym Full Names: | tubulin beta 2B class IIb |
| NCBI Official Symbol: | TUBB2B |
| NCBI Official Synonym Symbols: | PMGYSA; bA506K6.1 |
| NCBI Protein Information: | tubulin beta-2B chain |
| UniProt Protein Name: | Tubulin beta-2B chain |
| Protein Family: | Tubulin |
| UniProt Gene Name: | TUBB2B |
| UniProt Entry Name: | TBB2B_HUMAN |
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