TTYH2 Antibody (PACO63611)
- SKU:
- PACO63611
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | TTYH2 Antibody (PACO63611) |
| Antibody SKU: | PACO63611 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:1000-1:5000 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Protein tweety homolog 2 protein (455-534AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western Blot. Positive WB detected in Recombinant protein. All lanes: TTYH2 antibody at 1:2000. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 22.9 kDa. Observed band size: 28 kDa. |
| Background: | Probable large-conductance Ca2+-activated chloride channel. May play a role in Ca2+ signal transduction. May be involved in cell proliferation and cell aggregation. |
| Synonyms: | Protein tweety homolog 2, hTTY2, TTYH2, C17orf29 |
| UniProt Protein Function: | TTYH2: Probable large-conductance Ca(2+)-activated chloride channel. May play a role in Ca(2+) signal transduction. May be involved in cell proliferation and cell aggregation. Belongs to the tweety family. 2 isoforms of the human protein are produced by alternative splicing.Protein type: Membrane protein, integral; Channel, chloride; Transporter; Transporter, ion channel; Membrane protein, multi-passChromosomal Location of Human Ortholog: 17q25.1Cellular Component: plasma membraneMolecular Function: chloride channel activity; protein binding |
| UniProt Protein Details: | |
| NCBI Summary: | This gene encodes a member of the tweety family of proteins. Members of this family function as chloride anion channels. The encoded protein functions as a calcium(2+)-activated large conductance chloride(-) channel, and may play a role in kidney tumorigenesis. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q9BSA4 |
| NCBI GenInfo Identifier: | 53988385 |
| NCBI Gene ID: | 94015 |
| NCBI Accession: | NP_116035.5 |
| UniProt Secondary Accession: | Q9BSA4,Q3B7H8, Q3B7R9, Q6AWB4, Q8NBB7, Q96PK1, B3KX97 |
| UniProt Related Accession: | Q9BSA4 |
| Molecular Weight: | 23,562 Da |
| NCBI Full Name: | protein tweety homolog 2 isoform 1 |
| NCBI Synonym Full Names: | tweety family member 2 |
| NCBI Official Symbol: | TTYH2 |
| NCBI Official Synonym Symbols: | C17orf29 |
| NCBI Protein Information: | protein tweety homolog 2 |
| UniProt Protein Name: | Protein tweety homolog 2 |
| UniProt Synonym Protein Names: | |
| Protein Family: | Protein tweety |
| UniProt Gene Name: | TTYH2 |
| UniProt Entry Name: | TTYH2_HUMAN |
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