TTLL8 Antibody (PACO47730)
- SKU:
- PACO47730
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Applications:
- IF
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | TTLL8 Antibody (PACO47730) |
| Antibody SKU: | PACO47730 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC, IF |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200, IF:1:50-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Protein monoglycylase TTLL8 protein (671-822AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Immunohistochemistry of paraffin-embedded human lung tissue using PACO47730 at dilution of 1:100. |
 | Immunofluorescent analysis of Ntera-2 cells using PACO47730 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
| Background: | Monoglycylase which modifies both tubulin and non-tubulin proteins, generating side chains of glycine on the gamma-carboxyl groups of specific glutamate residues of target proteins. Monoglycylates tubulin, with a preference for alpha-tubulin toward beta-tubulin. Has the ability to modify non-tubulin proteins such as ANP32A, ANP32B, SET and NCL. Involved in the side-chain initiation step of the glycylation reaction by adding a single glycine chain to generate monoglycine side chains. Not involved in elongation step of the polyglycylation reaction (By similarity). |
| Synonyms: | Protein monoglycylase TTLL8 (EC 6.3.2) (Tubulin--tyrosine ligase-like protein 8), TTLL8 |
| UniProt Protein Function: | |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | A6PVC2 |
| NCBI GenInfo Identifier: | 325511405 |
| NCBI Gene ID: | 0 |
| NCBI Accession: | A6PVC2.4 |
| UniProt Secondary Accession: | A6PVC2,B5MDV0 |
| UniProt Related Accession: | A6PVC2 |
| Molecular Weight: | 94,676 Da |
| NCBI Full Name: | Protein monoglycylase TTLL8 |
| NCBI Synonym Full Names: | |
| NCBI Official Symbol: | |
| NCBI Official Synonym Symbols: | |
| NCBI Protein Information: | |
| UniProt Protein Name: | Protein monoglycylase TTLL8 |
| UniProt Synonym Protein Names: | Tubulin--tyrosine ligase-like protein 8 |
| Protein Family: | Protein monoglycylase |
| UniProt Gene Name: | TTLL8 |
| UniProt Entry Name: | TTLL8_HUMAN |
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