TTLL5 Antibody (PACO36350)
- SKU:
- PACO36350
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | TTLL5 Antibody (PACO36350) |
| Antibody SKU: | PACO36350 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA |
| Recommended Dilutions: | |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Tubulin polyglutamylase TTLL5 protein (1-269AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Background: | Polyglutamylase which preferentially modifies alpha-tubulin. Involved in the side-chain initiation step of the polyglutamylation reaction rather than in the elongation step (By similarity). Required for CCSAP localization to both spindle and cilia microtubules. Increases the effects of NCOA2 in glucocorticoid receptor-mediated repression and induction and in androgen receptor-mediated induction. |
| Synonyms: | Tubulin polyglutamylase TTLL5 (EC 6.-.-.-) (SRC1 and TIF2-associated modulatory protein) (Tubulin--tyrosine ligase-like protein 5), TTLL5, KIAA0998 STAMP |
| UniProt Protein Function: | |
| UniProt Protein Details: | |
| NCBI Summary: | This gene encodes an endo/exonuclease with 5'-3' exonuclease activity. The encoded enzyme catalyzes the hydrolysis of ester linkages at the 5' end of a nucleic acid chain. This enzyme is localized to the mitochondria and may play a role in programmed cell death. Alternatively spliced transcript variants have been described. A pseudogene exists on chromosome 18. [provided by RefSeq, Feb 2009] |
| UniProt Code: | Q6EMB2 |
| NCBI GenInfo Identifier: | 74353773 |
| NCBI Gene ID: | 9941 |
| NCBI Accession: | BC104212 |
| UniProt Secondary Accession: | Q6EMB2 |
| UniProt Related Accession: | Q6EMB2,Q9Y2C4 |
| Molecular Weight: | 41kDa |
| NCBI Full Name: | Homo sapiens endo/exonuclease (5'-3'), endonuclease G-like, mRNA |
| NCBI Synonym Full Names: | exo/endonuclease G |
| NCBI Official Symbol: | EXOG |
| NCBI Official Synonym Symbols: | ENGL; ENGLA; ENGLB; ENGL-a; ENGL-b; ENDOGL1; ENDOGL2 |
| NCBI Protein Information: | nuclease EXOG, mitochondrial |
| UniProt Protein Name: | Tubulin polyglutamylase TTLL5 |
| UniProt Synonym Protein Names: | SRC1 and TIF2-associated modulatory protein; Tubulin--tyrosine ligase-like protein 5 |
| Protein Family: | Exoglucanase |
| UniProt Gene Name: | TTLL5 |
| UniProt Entry Name: | TTLL5_HUMAN |
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