TTLL3 Antibody (PACO59960)
- SKU:
- PACO59960
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | TTLL3 Antibody (PACO59960) |
| Antibody SKU: | PACO59960 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:200-1:500 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Tubulin monoglycylase TTLL3 protein (470-641AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | IHC image of PACO59960 diluted at 1:300 and staining in paraffin-embedded human prostate cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system. |
 | IHC image of PACO59960 diluted at 1:300 and staining in paraffin-embedded human breast cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system. |
| Background: | Monoglycylase which modifies alpha- and beta-tubulin, generating side chains of glycine on the gamma-carboxyl groups of specific glutamate residues within the C-terminal tail of alpha- and beta-tubulin. Involved in the side-chain initiation step of the glycylation reaction by adding a single glycine chain to generate monoglycine side chains. Not involved in elongation step of the polyglycylation reaction. |
| Synonyms: | Tubulin monoglycylase TTLL3 (EC 6.3.2) (HOTTL) (Tubulin--tyrosine ligase-like protein 3), TTLL3 |
| UniProt Protein Function: | |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q9Y4R7 |
| NCBI GenInfo Identifier: | 649140031 |
| NCBI Gene ID: | 26140 |
| NCBI Accession: | AIC59944.1 |
| UniProt Secondary Accession: | Q9Y4R7 |
| UniProt Related Accession: | Q9Y4R7 |
| Molecular Weight: | 48kDa |
| NCBI Full Name: | TTLL3, partial |
| NCBI Synonym Full Names: | tubulin tyrosine ligase like 3 |
| NCBI Official Symbol: | TTLL3 |
| NCBI Official Synonym Symbols: | HOTTL |
| NCBI Protein Information: | tubulin monoglycylase TTLL3 |
| UniProt Protein Name: | |
| UniProt Synonym Protein Names: | |
| Protein Family: | Tubulin monoglycylase |
| UniProt Gene Name: | |
| UniProt Entry Name: |
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