Description
| Antibody Name: | TSR2 Antibody (PACO52566) |
| Antibody SKU: | PACO52566 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC, IF |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:200-1:5000, IHC:1:20-1:200, IF:1:50-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Pre-rRNA-processing protein TSR2 homolog protein (1-191AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
![]() | Immunohistochemistry of paraffin-embedded human lung tissue using PACO52566 at dilution of 1:100. |
![]() | Immunofluorescent analysis of MCF-7 cells using PACO52566 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
![]() | Immunohistochemistry of paraffin-embedded human heart tissue using PACO52566 at dilution of 1:100. |
| Background: | May be involved in 20S pre-rRNA processing. |
| Synonyms: | Pre-rRNA-processing protein TSR2 homolog, TSR2 |
| UniProt Protein Function: | TSR2: May be involved in 20S pre-rRNA processing (Potential). Belongs to the TSR2 family.Chromosomal Location of Human Ortholog: Xp11.22Cellular Component: nucleusMolecular Function: protein bindingBiological Process: maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)Disease: Diamond-blackfan Anemia 14 With Mandibulofacial Dysostosis |
| UniProt Protein Details: | |
| NCBI Summary: | The protein encoded by this gene appears to repress the transcription of NF-kappaB and may be involved in apoptosis. Defects in this gene are a cause of Diamond-Blackfan anemia. [provided by RefSeq, Oct 2016] |
| UniProt Code: | Q969E8 |
| NCBI GenInfo Identifier: | 24308388 |
| NCBI Gene ID: | 90121 |
| NCBI Accession: | NP_477511.1 |
| UniProt Secondary Accession: | Q969E8 |
| UniProt Related Accession: | Q969E8 |
| Molecular Weight: | 21 kDa |
| NCBI Full Name: | pre-rRNA-processing protein TSR2 homolog isoform a |
| NCBI Synonym Full Names: | TSR2 ribosome maturation factor |
| NCBI Official Symbol: | TSR2 |
| NCBI Official Synonym Symbols: | WGG1; DBA14; DT1P1A10 |
| NCBI Protein Information: | pre-rRNA-processing protein TSR2 homolog |
| UniProt Protein Name: | Pre-rRNA-processing protein TSR2 homolog |
| UniProt Synonym Protein Names: | |
| Protein Family: | Pre-rRNA-processing protein |
| UniProt Gene Name: | TSR2 |
| UniProt Entry Name: | TSR2_HUMAN |
| Antibodies |
| TSR2 Antibody (PACO12967) |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |


