Description
Product Name: | TSPAN32 Polyclonal Antibody |
Product Code: | CAB6323 |
Reactivity: | Human |
Applications: | Western blotting |
Host Species: | Rabbit |
Purification Method: | Affinity purification |
Isotype: | IgG |
Reactivity: | Human |
Tested Applications: | WB, ELISA |
Key Applications: | Western blotting |
Recommended Dilution: | WB 1:500-1:2000 |
Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Cellular Location: | Membrane, Multi-pass membrane protein |
This gene, which is a member of the tetraspanin superfamily, is one of several tumor-suppressing subtransferable fragments located in the imprinted gene domain of chromosome 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian and breast cancers. This gene is located among several imprinted genes; however, this gene, as well as the tumor-suppressing subchromosomal transferable fragment 4, escapes imprinting. This gene may play a role in malignancies and diseases that involve this region, and it is also involved in hematopoietic cell function. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 110-205 of human TSPAN32 (NP_620591.3). |
Sequence: | FWRLH SPTQV EDAML DTYDL VYEQA MKGTS HVRRQ ELAAI QDVFL CCGKK SPFSR LGSTE ADLCQ GEEAA REDCL QGIRS FLRTH QQVAS SLTSI G |
Synonyms: | ART1, PHMX, PHEMX, TSSC6 |
Calculated MW: | 35kDa |
Observed MW: | Refer to figures |