TSLP Monoclonal Antibody
- SKU:
- CAB24914
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
- Applications:
- IHC
- Applications:
- IF
Description
| Product Name: | TSLP Monoclonal Antibody |
| Product Code: | CAB24914 |
| Reactivity: | Human, Mouse |
| Applications: | Western blotting, Immunohistochemistry, Immunofluorescence |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC64624 |
| Reactivity: | Human, Mouse |
| Tested Applications: | WB, IHC-P, IF/ICC, ELISA |
| Key Applications: | Western blotting, Immunohistochemistry, Immunofluorescence |
| Recommended Dilution: | WB 1:500-1:1000, IHC-P 1:50-1:200, IF/ICC 1:50-1:200 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
| Positive Samples: | Recombinant protein of human TSLP |
| Cellular Location: | Secreted |
This gene encodes a hemopoietic cytokine proposed to signal through a heterodimeric receptor complex composed of the thymic stromal lymphopoietin receptor and the IL-7R alpha chain. It mainly impacts myeloid cells and induces the release of T cell-attracting chemokines from monocytes and enhances the maturation of CD11c(+) dendritic cells. The protein promotes T helper type 2 (TH2) cell responses that are associated with immunity in various inflammatory diseases, including asthma, allergic inflammation and chronic obstructive pulmonary disease. The protein is therefore considered a potential therapeutic target for the treatment of such diseases. In addition, the shorter (predominant) isoform is an antimicrobial protein, displaying antibacterial and antifungal activity against B. cereus, E. coli, E. faecalis, S. mitis, S. epidermidis, and C. albicans. Alternative splicing of this gene results in multiple transcript variants.
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to aminoacids 29-159 of human TSLP(NP_149024.1). |
| Sequence: | YDFTN CDFEK IKAAY LSTIS KDLIT YMSGT KSTEF NNTVS CSNRP HCLTE IQSLT FNPTA GCASL AKEMF AMKTK AALAI WCPGY SETQI NATQA MKKRR KRKVT TNKCL EQVSQ LQGLW RRFNR PLLKQ Q |
| Synonyms: | TSLP |
| Calculated MW: | 18kDa |
| Observed MW: | 20-30kDa |
Related Products
Anti-TSLP Chimeric Recombinant Rabbit Monoclonal Antibody (HDAB0270)
Tezepelumab (Anti-TSLP) Biosimilar Antibody
![TSLPR Monoclonal Antibody [PAT4E7A] (CPAB0075)](https://cdn11.bigcommerce.com/s-rd6ounxcu2/images/stencil/590x590/products/58303/63485/tslpr-monoclonal-antibody-pat4e7a-cpab0075__97988__78970.1706534964.jpg?c=1 "TSLPR Monoclonal Antibody [PAT4E7A] (CPAB0075)")