Description
Product Name: | TSC22D3 Polyclonal Antibody |
Product Code: | CAB24661 |
Reactivity: | Rat |
Applications: | Immunofluorescence |
Host Species: | Rabbit |
Purification Method: | Affinity purification |
Isotype: | IgG |
Reactivity: | Rat |
Tested Applications: | IF/ICC, ELISA |
Key Applications: | Immunofluorescence |
Recommended Dilution: | IF/ICC 1:50-1:200 |
Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 50% glycerol, pH7.3. |
Cellular Location: | Cytoplasm, Nucleus |
This gene encodes the anti-inflammatory protein glucocorticoid (GC)-induced leucine zipper. Expression of this gene stimulated by glucocorticoids and interleukin 10 and it appears to play a key role in the anti-inflammatory and immunosuppressive effects of this steroid. This protein has also been shown to inhibit pro-inflammatory molecules including nuclear factor κB. Alternate splicing results in multiple transcript variants.
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human TSC22D3 (NP_004080.2). |
Sequence: | MNTEM YQTPM EVAVY QLHNF SISFF SSLLG GDVVS VKLDN SASGA SVVAI DNKIE QAMDL VKNHL MYAVR EEVEI LKEQI RELVE KNSQL ERENT LLKTL |
Synonyms: | DIP, GILZ, DSIPI, TSC-22R |
Calculated MW: | 15kDa |
Observed MW: | Refer to figures |