TRPV4 Monoclonal Antibody
- SKU:
- CAB22657
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
- Applications:
- IHC
- Applications:
- IF
Description
| Product Name: | TRPV4 Monoclonal Antibody |
| Product Code: | CAB22657 |
| Reactivity: | Human, Mouse, Rat |
| Applications: | Western blotting, Immunohistochemistry, Immunofluorescence |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC58721 |
| Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB, IHC-P, IF/ICC, ELISA |
| Key Applications: | Western blotting, Immunohistochemistry, Immunofluorescence |
| Recommended Dilution: | WB 1:2000-1:6000, IHC-P 1:100-1:500, IF/ICC 1:50-1:200 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
| Positive Samples: | A375 |
| Cellular Location: | Apical cell membrane, Cell junction, Cell membrane, Cell projection, Multi-pass membrane protein, adherens junction, cilium |
This gene encodes a member of the OSM9-like transient receptor potential channel (OTRPC) subfamily in the transient receptor potential (TRP) superfamily of ion channels. The encoded protein is a Ca2+-permeable, nonselective cation channel that is thought to be involved in the regulation of systemic osmotic pressure. Mutations in this gene are the cause of spondylometaphyseal and metatropic dysplasia and hereditary motor and sensory neuropathy type IIC. Multiple transcript variants encoding different isoforms have been found for this gene.
| Immunogen: | A synthesized peptide derived from human TRPV4. |
| Sequence: | LTFVL LLNML IALMG ETVGQ VSKES KHIWK LQWAT TILDI ERSFP VFLRK AFRSG EMVTV GKSSD GTPDR RWCFR VDEVN WSHWN QNLGI INEDP GKNET YQYYG FSHTV GRLRR DRWSS VVPRV VELNK NSNPD EVVVP LDSMG NPRCD GHQQG YPRKW RTDDA PL |
| Synonyms: | SMAL, VRL2, BCYM3, CMT2C, SPSMA, TRP12, VROAC, HMSN2C, OTRPC4, SSQTL1 |
| Calculated MW: | 98kDa |
| Observed MW: | Refer to figures |
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