Description
Product Name: | TRPV1 Monoclonal Antibody |
Product Code: | CAB23386 |
Reactivity: | Mouse, Rat |
Applications: | Western blotting |
Host Species: | Rabbit |
Purification Method: | Affinity purification |
Isotype: | IgG |
Clone No: | ARC57842 |
Reactivity: | Mouse, Rat |
Tested Applications: | WB, ELISA |
Key Applications: | Western blotting |
Recommended Dilution: | WB 1:500-1:1000 |
Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
Positive Samples: | Mouse brain, Rat brain |
Cellular Location: | Cell junction, Cell membrane, Cell projection, dendritic spine membrane, postsynaptic cell membrane, synaps |
Capsaicin, the main pungent ingredient in hot chili peppers, elicits a sensation of burning pain by selectively activating sensory neurons that convey information about noxious stimuli to the central nervous system. The protein encoded by this gene is a receptor for capsaicin and is a non-selective cation channel that is structurally related to members of the TRP family of ion channels. This receptor is also activated by increases in temperature in the noxious range, suggesting that it functions as a transducer of painful thermal stimuli in vivo. Four transcript variants encoding the same protein, but with different 5' UTR sequence, have been described for this gene.
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 725-839 of human TRPV1 (NP_542435.2). |
Sequence: | KLLQV GYTPD GKDDY RWCFR VDEVN WTTWN TNVGI INEDP GNCEG VKRTL SFSLR SSRVS GRHWK NFALV PLLRE ASARD RQSAQ PEEVY LRQFS GSLKP EDAEV FKSPA ASGEK |
Synonyms: | VR1 |
Calculated MW: | 95kDa |
Observed MW: | 100kDa |