TRPM3 Antibody (PACO60396)
- SKU:
- PACO60396
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IF
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | TRPM3 Antibody (PACO60396) |
| Antibody SKU: | PACO60396 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IF |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IF:1:50-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Transient receptor potential cation channel subfamily M member 3 protein (1606-1713AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Immunofluorescence staining of Hela cells with PACO60396 at 1:133, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
| Background: | Calcium channel mediating constitutive calcium ion entry. Its activity is increased by reduction in extracellular osmolarity, by store depletion and muscarinic receptor activation. |
| Synonyms: | Transient receptor potential cation channel subfamily M member 3 (Long transient receptor potential channel 3) (LTrpC-3) (LTrpC3) (Melastatin-2) (MLSN2), TRPM3, KIAA1616 LTRPC3 |
| UniProt Protein Function: | TRPM3: a transient receptor potential (TRP) ion channel. Mediates constitutive calcium ion entry. Its activity is increased by reduction in extracellular osmolarity, by calcium store depletion and muscarinic receptor activation. TRP voltage-independent calcium-permeable cation channels are divided into six subfamilies, two of which (TRPC and TRPM) have members that are widely expressed. Ten alternatively spliced isoforms have been described.Protein type: Channel, cation; Membrane protein, integral; Membrane protein, multi-passChromosomal Location of Human Ortholog: 9q21.12-q21.13Cellular Component: integral component of membrane; plasma membraneMolecular Function: calcium activated cation channel activity; calcium channel activity; cation channel activityBiological Process: cation transport; detection of temperature stimulus; protein tetramerization; sensory perception of temperature stimulus |
| UniProt Protein Details: | |
| NCBI Summary: | The product of this gene belongs to the family of transient receptor potential (TRP) channels. TRP channels are cation-selective channels important for cellular calcium signaling and homeostasis. The protein encoded by this gene mediates calcium entry, and this entry is potentiated by calcium store depletion. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q9HCF6 |
| NCBI GenInfo Identifier: | 581985920 |
| NCBI Gene ID: | 80036 |
| NCBI Accession: | AHI18585.1 |
| UniProt Secondary Accession: | Q9HCF6,Q5VW02, Q5VW03, Q5VW04, Q5W5T7, Q86SH0, Q86SH6 Q86UL0, Q86WK1, Q86WK2 |
| UniProt Related Accession: | Q9HCF6 |
| Molecular Weight: | 25,159 Da |
| NCBI Full Name: | transient receptor potential cation channel subfamily M member 3, partial |
| NCBI Synonym Full Names: | transient receptor potential cation channel subfamily M member 3 |
| NCBI Official Symbol: | TRPM3 |
| NCBI Official Synonym Symbols: | GON-2; MLSN2; LTRPC3 |
| NCBI Protein Information: | transient receptor potential cation channel subfamily M member 3 |
| UniProt Protein Name: | Transient receptor potential cation channel subfamily M member 3 |
| UniProt Synonym Protein Names: | Long transient receptor potential channel 3; LTrpC-3; LTrpC3; Melastatin-2; MLSN2 |
| Protein Family: | Transient receptor potential cation channel subfamily |
| UniProt Gene Name: | TRPM3 |
| UniProt Entry Name: |
Related Products
HS3ST3B1 Antibody
Overview Product Name:HS3ST3B1 AntibodyProduct Code:PACO64781Size:50µLTarget Names:HS3ST3B1Species Reactivity:Human<
hns Antibody
Overview Product Name:hns AntibodyProduct Code:PACO64777Size:50µLTarget Names:hnsSpecies Reactivity:Escherichia coli
Avpr1b Antibody
Overview Product Name:Avpr1b AntibodyProduct Code:PACO64609Size:50µLTarget Names:Avpr1bSpecies Reactivity:RatHos
SEZ6 Antibody
Overview Product Name:SEZ6 AntibodyProduct Code:PACO64941Size:50µLTarget Names:SEZ6Species Reactivity:HumanHost