TRPC4AP Antibody (PACO12939)
- SKU:
- PACO12939
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | TRPC4AP Antibody (PACO12939) |
| Antibody SKU: | PACO12939 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC |
| Recommended Dilutions: | |
| Species Reactivity: | Human, Mouse, Rat |
| Immunogen: | Human TRPC4AP |
| Form: | Liquid |
| Storage Buffer: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
| Purification Method: | Antigen Affinity Purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Synonyms: | transient receptor potential cation channel, subfamily C, member 4 associated protein;TRPC4AP;C20orf188;TRRP4AP;TRUSS ; |
| UniProt Protein Function: | TRPC4AP: Substrate-specific adapter of a DCX (DDB1-CUL4-X-box) E3 ubiquitin-protein ligase complex required for cell cycle control. The DCX(TRUSS) complex specifically mediates the polyubiquitination and subsequent degradation of MYC. Also participates in the activation of NFKB1 in response to ligation of TNFRSF1A, possibly by linking TNFRSF1A to the IKK signalosome. Involved in JNK activation via its interaction with TRAF2. Also involved in elevation of endoplasmic reticulum Ca(2+) storage reduction in response to CHRM1. 2 isoforms of the human protein are produced by alternative splicing.Protein type: Adaptor/scaffoldChromosomal Location of Human Ortholog: 20q11.22Cellular Component: plasma membraneMolecular Function: calcium channel activity; phosphatase binding; protein bindingBiological Process: protein ubiquitination; ubiquitin-dependent protein catabolic process |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q8TEL6 |
| NCBI GenInfo Identifier: | 25091357 |
| NCBI Gene ID: | 26133 |
| NCBI Accession: | Q8TEL6.2 |
| UniProt Secondary Accession: | Q8TEL6,Q96H82, Q9BVB8, Q9H429, Q9UFS6, E1P5Q0, E1P5Q1 |
| UniProt Related Accession: | Q8TEL6 |
| Molecular Weight: | 90,043 Da |
| NCBI Full Name: | Short transient receptor potential channel 4-associated protein |
| NCBI Synonym Full Names: | transient receptor potential cation channel subfamily C member 4 associated protein |
| NCBI Official Symbol: | TRPC4AP |
| NCBI Official Synonym Symbols: | TRUSS; TRRP4AP; PPP1R158; C20orf188 |
| NCBI Protein Information: | short transient receptor potential channel 4-associated protein |
| UniProt Protein Name: | Short transient receptor potential channel 4-associated protein |
| UniProt Synonym Protein Names: | Protein TAP1; TNF-receptor ubiquitous scaffolding/signaling protein; Protein TRUSS |
| Protein Family: | Short transient receptor potential channel 4-associated protein |
| UniProt Gene Name: | TRPC4AP |
| UniProt Entry Name: | TP4AP_HUMAN |
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