TrkB Monoclonal Antibody (CAB21227)
- SKU:
- CAB21227
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Description
| Product Name: | TrkB Monoclonal Antibody |
| Product Code: | CAB21227 |
| Reactivity: | Mouse, Rat |
| Applications: | Western blotting |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC53483 |
| Reactivity: | Mouse, Rat |
| Tested Applications: | WB, ELISA |
| Key Applications: | Western blotting |
| Recommended Dilution: | WB 1:2000-1:20000 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
| Positive Samples: | Mouse brain, Rat brain |
| Cellular Location: | Cell membrane, Endosome membrane, Single-pass type I membrane protein |
This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation. Mutations in this gene have been associated with obesity and mood disorders. Alternative splicing results in multiple transcript variants.
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 32-430 of human TrkB (NP_001018074.1). |
| Sequence: | CPTSC KCSAS RIWCS DPSPG IVAFP RLEPN SVDPE NITEI FIANQ KRLEI INEDD VEAYV GLRNL TIVDS GLKFV AHKAF LKNSN LQHIN FTRNK LTSLS RKHFR HLDLS ELILV GNPFT CSCDI MWIKT LQEAK SSPDT QDLYC LNESS KNIPL ANLQI PNCGL PSANL AAPNL TVEEG KSITL SCSVA GDPVP NMYWD VGNLV SKHMN ETSHT QGSLR ITNIS SDDSG KQISC VAENL VGEDQ DSVNL TVHFA PTITF LESPT SDHHW CIPFT VKGNP KPALQ WFYNG AILNE SKYIC TKIHV TNHTE YHGCL QLDNP THMNN GDYTL IAKNE YGKDE KQISA HFMGW PGIDD GANPN YPDVI YEDYG TAAND IGDTT NRSNE IPSTD VTDKT GREH |
| Synonyms: | OBHD, TRKB, DEE58, trk-B, EIEE58, GP145-TrkB |
| Calculated MW: | 92kDa |
| Observed MW: | 90kDa/140kDa |
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