TRIP6 Antibody (PACO12929)
- SKU:
- PACO12929
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Applications:
- IF
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | TRIP6 Antibody (PACO12929) |
| Antibody SKU: | PACO12929 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IF |
| Recommended Dilutions: | |
| Species Reactivity: | Human, Mouse, Rat |
| Immunogen: | Human TRIP6 |
| Form: | Liquid |
| Storage Buffer: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
| Purification Method: | Antigen Affinity purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Synonyms: | thyroid hormone receptor interactor 6;TRIP6;MGC10556;MGC10558;MGC29959;MGC3837;MGC4423;OIP1;ZRP-1 ; |
| UniProt Protein Function: | TRIP6: thyroid receptor interacting protein 6 specifically interacts with the ligand-binding domain of the thyroid receptor (TR). Requires the presence of thyroid hormone for its interaction. Interacts with PTPN13. Functions downstream of the activated LPA(2) receptor and is involved in cell adhesion and migration.Protein type: Nuclear receptor co-regulator; Motility/polarity/chemotaxis; Adaptor/scaffoldChromosomal Location of Human Ortholog: 7q22Cellular Component: interleukin-1 receptor complex; cytoskeleton; focal adhesion; cytoplasm; plasma membrane; nucleusMolecular Function: protein binding; interleukin-1 receptor binding; zinc ion binding; thyroid hormone receptor binding; kinase bindingBiological Process: release of cytoplasmic sequestered NF-kappaB; focal adhesion formation; regulation of transcription, DNA-dependent; transcription, DNA-dependent; positive regulation of cell migration |
| UniProt Protein Details: | |
| NCBI Summary: | This gene is a member of the zyxin family and encodes a protein with three LIM zinc-binding domains. This protein localizes to focal adhesion sites and along actin stress fibers. Recruitment of this protein to the plasma membrane occurs in a lysophosphatidic acid (LPA)-dependent manner and it regulates LPA-induced cell migration. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q15654 |
| NCBI GenInfo Identifier: | 20981729 |
| NCBI Gene ID: | 7205 |
| NCBI Accession: | Q15654.3 |
| UniProt Secondary Accession: | Q15654,O15170, O15275, Q9BTB2, Q9BUE5, Q9BXP3, Q9UNT4 A4D2E7, F2ZC07, F2ZC08 |
| UniProt Related Accession: | Q15654 |
| Molecular Weight: | 476 |
| NCBI Full Name: | Thyroid receptor-interacting protein 6 |
| NCBI Synonym Full Names: | thyroid hormone receptor interactor 6 |
| NCBI Official Symbol: | TRIP6 |
| NCBI Official Synonym Symbols: | OIP1; OIP-1; ZRP-1; TRIP-6; TRIP6i2 |
| NCBI Protein Information: | thyroid receptor-interacting protein 6; zyxin related protein 1; TR-interacting protein 6; OPA-interacting protein 1; thyroid hormone receptor interacting protein 6 |
| UniProt Protein Name: | Thyroid receptor-interacting protein 6 |
| UniProt Synonym Protein Names: | Opa-interacting protein 1; OIP-1; Zyxin-related protein 1; ZRP-1 |
| Protein Family: | Thyroid receptor-interacting protein |
| UniProt Gene Name: | TRIP6 |
| UniProt Entry Name: | TRIP6_HUMAN |
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