Antibody Name:	TRIM34 Antibody (PACO20356)
Antibody SKU:	PACO20356
Size:	50ul
Host Species:	Rabbit
Tested Applications:	ELISA, WB, IHC
Recommended Dilutions:	ELISA:1:1000-1:2000, WB:1:200-1:1000, IHC:1:25-1:100
Species Reactivity:	Human
Immunogen:	Synthetic peptide of human TRIM34

Form:	Liquid
Storage Buffer:	-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification Method:	Antigen affinity purification
Clonality:	Polyclonal
Isotype:	IgG
Conjugate:	Non-conjugated

	The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using PACO20356(TRIM34 Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: x200).
	Gel: 8%SDS-PAGE, Lysate: 40 µg, Lane: Jurkat cells, Primary antibody: PACO20356(TRIM34 Antibody) at dilution 1/250, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 40 seconds.
	The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using PACO20356(TRIM34 Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: x200).

Background:

The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, B-box type 1 and B-box type 2 domain, and a coiled-coil region. Expression of this gene is up-regulated by interferon. This gene is mapped to chromosome 11p15, where it resides within a TRIM gene cluster. Alternative splicing results in multiple transcript variants. A read-through transcript from the upstream TRIM6 gene has also been observed, which results in a fusion product from these neighboring family members.

Synonyms:

tripartite motif containing 34

UniProt Protein Function:	TRIM34: is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, B-box type 1 and B-box type 2 domain, and a coiled-coil region. Expression of this gene is up-regulated by interferon. This gene is mapped to chromosome 11p15, where it resides within a TRIM gene cluster. Alternative splicing results in multiple transcript variants. A read-through transcript from the upstream TRIM6 gene has also been observed, which results in a fusion product from these neighboring family members. [provided by RefSeq, Oct 2010]Protein type: Ubiquitin conjugating systemChromosomal Location of Human Ortholog: 11p15Cellular Component: cytoplasm; cytosolBiological Process: positive regulation of transcription factor activity
UniProt Protein Details:
NCBI Summary:	The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, B-box type 1 and B-box type 2 domain, and a coiled-coil region. Expression of this gene is up-regulated by interferon. This gene is mapped to chromosome 11p15, where it resides within a TRIM gene cluster. Alternative splicing results in multiple transcript variants. A read-through transcript from the upstream TRIM6 gene has also been observed, which results in a fusion product from these neighboring family members. [provided by RefSeq, Oct 2010]
UniProt Code:	Q9BYJ4
NCBI GenInfo Identifier:	55976584
NCBI Gene ID:	53840
NCBI Accession:	Q9BYJ4.2
UniProt Secondary Accession:	Q9BYJ4,Q9C016, Q9HCR0, Q9HCR1, Q9HCR2, D3DQS7
UniProt Related Accession:	Q9BYJ4
Molecular Weight:	31,338 Da
NCBI Full Name:	Tripartite motif-containing protein 34
NCBI Synonym Full Names:	tripartite motif containing 34
NCBI Official Symbol:	TRIM34
NCBI Official Synonym Symbols:	IFP1; RNF21
NCBI Protein Information:	tripartite motif-containing protein 34
UniProt Protein Name:	Tripartite motif-containing protein 34
UniProt Synonym Protein Names:	Interferon-responsive finger protein 1; RING finger protein 21
Protein Family:	Tripartite motif-containing protein
UniProt Gene Name:	TRIM34
UniProt Entry Name:	TRI34_HUMAN