TRIM21/SS-A Monoclonal Antibody (CAB24737)
- SKU:
- CAB24737
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Description
| Product Name: | TRIM21/SS-A Monoclonal Antibody |
| Product Code: | CAB24737 |
| Reactivity: | Human, Rat |
| Applications: | Western blotting |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC64169 |
| Reactivity: | Human, Rat |
| Tested Applications: | WB, ELISA |
| Key Applications: | Western blotting |
| Recommended Dilution: | WB 1:500-1:1000 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
| Positive Samples: | HeLa, 293T, Rat lung |
| Cellular Location: | Cytoplasm, Cytoplasmic vesicle, Nucleus, P-body, autophagosome |
This gene encodes a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The encoded protein is part of the RoSSA ribonucleoprotein, which includes a single polypeptide and one of four small RNA molecules. The RoSSA particle localizes to both the cytoplasm and the nucleus. RoSSA interacts with autoantigens in patients with Sjogren syndrome and systemic lupus erythematosus. Alternatively spliced transcript variants for this gene have been described but the full-length nature of only one has been determined.
| Immunogen: | Recombinant Protein corresponding to a sequence within amino acids 86-334 of human TRIM21 (NP_003361.1). |
| Sequence: | GTQGE RCAVH GERLH LFCEK DGKAL CWVCA QSRKH RDHAM VPLEE AAQEY QEKLQ VALGE LRRKQ ELAEK LEVEI AIKRA DWKKT VETQK SRIHA EFVQQ KNFLV EEEQR QLQEL EKDER EQLRI LGEKE AKLAQ QSQAL QELIS ELDRR CHSSA LELLQ EVIIV LERSE SWNLK DLDIT SPELR SVCHV PGLKK MLRTC AVHIT LDPDT ANPWL ILSED RRQVR LGDTQ QSIPG NEERF DSYPM VLGA |
| Synonyms: | SSA, RO52, SSA1, RNF81, Ro/SSA |
| Calculated MW: | 54kDa |
| Observed MW: | 54kDa, 60kDa |
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