TRIM21/SS-A Monoclonal Antibody (CAB22724)
- SKU:
- CAB22724
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Description
| Product Name: | TRIM21/SS-A Monoclonal Antibody |
| Product Code: | CAB22724 |
| Reactivity: | Human |
| Applications: | Western blotting |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC57363 |
| Reactivity: | Human |
| Tested Applications: | WB, ELISA |
| Key Applications: | Western blotting |
| Recommended Dilution: | WB 1:1000-1:5000 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
| Positive Samples: | HT-1080, 293T |
| Cellular Location: | Cytoplasm, Cytoplasmic vesicle, Nucleus, P-body, autophagosome |
This gene encodes a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The encoded protein is part of the RoSSA ribonucleoprotein, which includes a single polypeptide and one of four small RNA molecules. The RoSSA particle localizes to both the cytoplasm and the nucleus. RoSSA interacts with autoantigens in patients with Sjogren syndrome and systemic lupus erythematosus. Alternatively spliced transcript variants for this gene have been described but the full-length nature of only one has been determined.
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 251-350 of human TRIM21/SS-A(NP_003132.2). |
| Sequence: | LERSE SWNLK DLDIT SPELR SVCHV PGLKK MLRTC AVHIT LDPDT ANPWL ILSED RRQVR LGDTQ QSIPG NEERF DSYPM VLGAQ HFHSG KHYWE VDVTG |
| Synonyms: | SSA, RO52, SSA1, RNF81, Ro/SSA |
| Calculated MW: | 54kDa |
| Observed MW: | 50kDa |
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