TRIM14 Antibody (PACO20691)
- SKU:
- PACO20691
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | TRIM14 Antibody (PACO20691) |
| Antibody SKU: | PACO20691 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:5000, IHC:1:25-1:100 |
| Species Reactivity: | Human |
| Immunogen: | Synthetic peptide of human TRIM14 |
| Form: | Liquid |
| Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Purification Method: | Antigen affinity purification |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using PACO20691(TRIM14 Antibody) at dilution 1/35, on the right is treated with synthetic peptide. (Original magnification: x200). |
| Background: | The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to cytoplasmic bodies and its function has not been determined. Alternative splicing results in multiple transcript variants. |
| Synonyms: | tripartite motif containing 14 |
| UniProt Protein Function: | TRIM14: Inhibits the transcriptional activity of SPI1 in a dose- dependent manner. Belongs to the TRIM/RBCC family. 4 isoforms of the human protein are produced by alternative splicing.Protein type: Transcription regulationChromosomal Location of Human Ortholog: 9q22.33Cellular Component: cytoplasm; intracellularMolecular Function: zinc ion bindingBiological Process: negative regulation of viral transcription; innate immune response; positive regulation of transcription factor activity; activation of NF-kappaB transcription factor |
| UniProt Protein Details: | |
| NCBI Summary: | The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to cytoplasmic bodies and its function has not been determined. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2010] |
| UniProt Code: | Q14142 |
| NCBI GenInfo Identifier: | 15208663 |
| NCBI Gene ID: | 9830 |
| NCBI Accession: | NP_055603.2 |
| UniProt Secondary Accession: | Q14142,Q548W9, Q5TBQ8, Q6ZWL7, Q9BRD8, Q9C020, A8K9W0 E7EQC4, F8W956 |
| UniProt Related Accession: | Q14142 |
| Molecular Weight: | |
| NCBI Full Name: | tripartite motif-containing protein 14 |
| NCBI Synonym Full Names: | tripartite motif containing 14 |
| NCBI Official Symbol: | TRIM14 |
| NCBI Official Synonym Symbols: | |
| NCBI Protein Information: | tripartite motif-containing protein 14 |
| UniProt Protein Name: | Tripartite motif-containing protein 14 |
| UniProt Synonym Protein Names: | |
| Protein Family: | Tripartite motif-containing protein |
| UniProt Gene Name: | TRIM14 |
| UniProt Entry Name: | TRI14_HUMAN |
| Antibodies |
| TRIM14 Antibody (PACO12903) |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
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