Description
Antibody Name: | TRIM14 Antibody (PACO17253) |
Antibody SKU: | PACO17253 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC |
Recommended Dilutions: | ELISA:1:2000-1:5000, WB:1:500-1:2000, IHC:1:30-1:150 |
Species Reactivity: | Human, Mouse |
Immunogen: | Fusion protein of human TRIM14 |
Form: | Liquid |
Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Purification Method: | Antigen affinity purification |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Gel: 8%SDS-PAGE,Lysate: 40 μg,,Primary antibody: PACO17253(TRIM14 Antibody) at dilution 1/800 dilution,Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution,Exposure time: 3 seconds. | |
The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using PACO17253(TRIM14 Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: x200). |
Background: | The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to cytoplasmic bodies and its function has not been determined. Alternative splicing results in multiple transcript variants. |
Synonyms: | tripartite motif containing 14 |
UniProt Protein Function: | TRIM14: Inhibits the transcriptional activity of SPI1 in a dose- dependent manner. Belongs to the TRIM/RBCC family. 4 isoforms of the human protein are produced by alternative splicing.Protein type: Transcription regulationChromosomal Location of Human Ortholog: 9q22.33Cellular Component: cytoplasm; intracellularMolecular Function: zinc ion bindingBiological Process: negative regulation of viral transcription; innate immune response; positive regulation of transcription factor activity; activation of NF-kappaB transcription factor |
UniProt Protein Details: | |
NCBI Summary: | The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to cytoplasmic bodies and its function has not been determined. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2010] |
UniProt Code: | Q14142 |
NCBI GenInfo Identifier: | 15208663 |
NCBI Gene ID: | 9830 |
NCBI Accession: | NP_055603.2 |
UniProt Secondary Accession: | Q14142,Q548W9, Q5TBQ8, Q6ZWL7, Q9BRD8, Q9C020, A8K9W0 E7EQC4, F8W956 |
UniProt Related Accession: | Q14142 |
Molecular Weight: | |
NCBI Full Name: | tripartite motif-containing protein 14 |
NCBI Synonym Full Names: | tripartite motif containing 14 |
NCBI Official Symbol: | TRIM14 |
NCBI Official Synonym Symbols: | |
NCBI Protein Information: | tripartite motif-containing protein 14 |
UniProt Protein Name: | Tripartite motif-containing protein 14 |
UniProt Synonym Protein Names: | |
Protein Family: | Tripartite motif-containing protein |
UniProt Gene Name: | TRIM14 |
UniProt Entry Name: | TRI14_HUMAN |
Antibodies |
TRIM14 Antibody (PACO12903) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |