TRIB3 Monoclonal Antibody
- SKU:
- CAB3523
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Description
| Product Name: | TRIB3 Monoclonal Antibody |
| Product Code: | CAB3523 |
| Reactivity: | Human |
| Applications: | Western blotting |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC2685 |
| Reactivity: | Human |
| Tested Applications: | WB, ELISA |
| Key Applications: | Western blotting |
| Recommended Dilution: | WB 1:500-1:1000 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
| Positive Samples: | K-562 |
| Cellular Location: | Nucleus |
The protein encoded by this gene is a putative protein kinase that is induced by the transcription factor NF-kappaB. The encoded protein is a negative regulator of NF-kappaB and can also sensitize cells to TNF- and TRAIL-induced apoptosis. In addition, this protein can negatively regulate the cell survival serine-threonine kinase AKT1. Differential promoter usage and alternate splicing result in multiple transcript variants.
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human TRIB3(Q96RU7) |
| Sequence: | MRATP LAAPA GSLSR KKRLE LDDNL DTERP VQKRA RSGPQ PRLPP CLLPL SPPTA PDRAT AVATA SRLGP YVLLE PEEGG |
| Synonyms: | NIPK, SINK, TRB3, SKIP3, C20orf97 |
| Calculated MW: | 40kDa |
| Observed MW: | 43kDa |
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