TRIB1 Antibody (PACO20762)
- SKU:
- PACO20762
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | TRIB1 Antibody (PACO20762) |
| Antibody SKU: | PACO20762 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:1000-1:2000, IHC:1:10-1:50 |
| Species Reactivity: | Human, Mouse |
| Immunogen: | Synthetic peptide of human TRIB1 |
| Form: | Liquid |
| Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Purification Method: | Antigen affinity purification |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using PACO20762(TRIB1 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: x200). |
| Background: | Interacts with MAPK kinases and regulates activation of MAP kinases. May not display kinase activity. |
| Synonyms: | tribbles pseudokinase 1 |
| UniProt Protein Function: | TRB1: Interacts with MAPK kinases and regulates activation of MAP kinases. May not display kinase activity. Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. Tribbles subfamily. |
| UniProt Protein Details: | Protein type:Protein kinase, Ser/Thr (non-receptor); Kinase, protein; Protein kinase, CAMK; CAMK group; Trbl family Chromosomal Location of Human Ortholog: 8q24.13 Cellular Component: cytoplasm; nucleus Molecular Function:ATP binding; mitogen-activated protein kinase kinase binding; protein binding; protein kinase activity; protein kinase inhibitor activity; transcription factor binding; ubiquitin protein ligase binding; ubiquitin-protein ligase regulator activity Biological Process: JNK cascade; negative regulation of lipopolysaccharide-mediated signaling pathway; negative regulation of protein kinase activity; negative regulation of smooth muscle cell migration; negative regulation of smooth muscle cell proliferation; negative regulation of transcription factor activity; positive regulation of proteasomal ubiquitin-dependent protein catabolic process; protein amino acid phosphorylation; regulation of MAP kinase activity; response to lipopolysaccharide |
| UniProt Code: | Q96RU8 |
| NCBI GenInfo Identifier: | 83305929 |
| NCBI Gene ID: | 10221 |
| NCBI Accession: | Q96RU8.2 |
| UniProt Secondary Accession: | Q96RU8,O15180, Q9H2Y8, B4DMM6, C5HU08, |
| UniProt Related Accession: | Q96RU8 |
| Molecular Weight: | 23,473 Da |
| NCBI Full Name: | Tribbles homolog 1 |
| NCBI Synonym Full Names: | tribbles pseudokinase 1 |
| NCBI Official Symbol: | TRIB1 |
| NCBI Official Synonym Symbols: | C8FW; GIG2; TRB1; GIG-2; SKIP1; TRB-1 |
| NCBI Protein Information: | tribbles homolog 1 |
| UniProt Protein Name: | Tribbles homolog 1 |
| UniProt Synonym Protein Names: | G-protein-coupled receptor-induced gene 2 protein; GIG-2; SKIP1 |
| UniProt Gene Name: | TRIB1 |
| UniProt Entry Name: | TRIB1_HUMAN |
| Antibodies |
| Anti-TRIB1 Antibody (CAB10134) |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
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