TREML2 Antibody (PACO36538)
- SKU:
- PACO36538
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | TREML2 Antibody (PACO36538) |
| Antibody SKU: | PACO36538 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Trem-like transcript 2 protein (19-268AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Immunohistochemistry of paraffin-embedded human colon cancer using PACO36538 at dilution of 1:100. |
 | Immunohistochemistry of paraffin-embedded human adrenal gland tissue using PACO36538 at dilution of 1:100. |
| Background: | Cell surface receptor that may play a role in the innate and adaptive immune response. Acts as a counter-receptor for CD276 and interaction with CD276 on T-cells enhances T-cell activation. |
| Synonyms: | Trem-like transcript 2 protein (TLT-2) (Triggering receptor expressed on myeloid cells-like protein 2), TREML2, C6orf76 TLT2 |
| UniProt Protein Function: | TREML2: Cell surface receptor that may play a role in the innate and adaptive immune response. Acts as a counter-receptor for CD276 and interaction with CD276 on T-cells enhances T-cell activation.Protein type: Membrane protein, integralChromosomal Location of Human Ortholog: 6p21.1Cellular Component: cell surface; integral to membrane; plasma membraneMolecular Function: protein binding; receptor activityBiological Process: T cell activation |
| UniProt Protein Details: | |
| NCBI Summary: | TREML2 is located in a gene cluster on chromosome 6 with the single Ig variable (IgV) domain activating receptors TREM1 (MIM 605085) and TREM2 (MIM 605086), but it has distinct structural and functional properties (Allcock et al., 2003 [PubMed 12645956]).[supplied by OMIM, Mar 2008] |
| UniProt Code: | Q5T2D2 |
| NCBI GenInfo Identifier: | 170932501 |
| NCBI Gene ID: | 79865 |
| NCBI Accession: | NP_079083.2 |
| UniProt Secondary Accession: | Q5T2D2 |
| UniProt Related Accession: | Q5T2D2 |
| Molecular Weight: | |
| NCBI Full Name: | trem-like transcript 2 protein |
| NCBI Synonym Full Names: | triggering receptor expressed on myeloid cells like 2 |
| NCBI Official Symbol: | TREML2 |
| NCBI Official Synonym Symbols: | TLT2; TLT-2; C6orf76; dJ238O23.1 |
| NCBI Protein Information: | trem-like transcript 2 protein |
| UniProt Protein Name: | Trem-like transcript 2 protein |
| UniProt Synonym Protein Names: | Triggering receptor expressed on myeloid cells-like protein 2 |
| Protein Family: | |
| UniProt Gene Name: | TREML2 |
| UniProt Entry Name: | TRML2_HUMAN |
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