Description
Product Name: | TREM2 Monoclonal Antibody |
Product Code: | CAB23432 |
Reactivity: | Mouse |
Applications: | Western blotting |
Host Species: | Rabbit |
Purification Method: | Affinity purification |
Isotype: | IgG |
Clone No: | ARC59142 |
Reactivity: | Mouse |
Tested Applications: | WB, ELISA |
Key Applications: | Western blotting |
Recommended Dilution: | WB 1:2000-1:9000 |
Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
Positive Samples: | Mouse heart |
Cellular Location: | Cell membrane, Secreted, Single-pass type I membrane protein |
This gene encodes a membrane protein that forms a receptor signaling complex with the TYRO protein tyrosine kinase binding protein. The encoded protein functions in immune response and may be involved in chronic inflammation by triggering the production of constitutive inflammatory cytokines. Defects in this gene are a cause of polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy (PLOSL). Alternative splicing results in multiple transcript variants encoding different isoforms.
Immunogen: | Recombinant protein of human TREM2. |
Sequence: | Email for sequence |
Synonyms: | PLOSL2, TREM-2, Trem2a, Trem2b, Trem2c |
Calculated MW: | 25kDa |
Observed MW: | 30kDa |