TREM2 Monoclonal Antibody (CAB22134)

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SKU:
CAB22134
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Applications:
WB

Description

Product Name:TREM2 Monoclonal Antibody
Product Code:CAB22134
Reactivity:Human
Applications:Western blotting
Host Species:Rabbit
Purification Method:Affinity purification
Isotype:IgG
Clone No:ARC55114
Reactivity:Human
Tested Applications:WB, ELISA
Key Applications:Western blotting
Recommended Dilution:WB 1:2000-1:10000
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3.
Positive Samples:HUH-7
Cellular Location:extracellular region, plasma membrane, plasma membrane raft

This gene encodes a membrane protein that forms a receptor signaling complex with the TYRO protein tyrosine kinase binding protein. The encoded protein functions in immune response and may be involved in chronic inflammation by triggering the production of constitutive inflammatory cytokines. Defects in this gene are a cause of polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy (PLOSL). Alternative splicing results in multiple transcript variants encoding different isoforms.

Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 19-161 of human TREM2 (NP_061838.1).
Sequence:HNTTV FQGVA GQSLQ VSCPY DSMKH WGRRK AWCRQ LGEKG PCQRV VSTHN LWLLS FLRRW NGSTA ITDDT LGGTL TITLR NLQPH DAGLY QCQSL HGSEA DTLRK VLVEV LADPL DHRDA GDLWF PGESE SFEDA HVEHS ISR
Synonyms:PLOSL2, TREM-2, Trem2a, Trem2b, Trem2c
Calculated MW:25kDa
Observed MW:35-50kDa
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