TRAPPC11 Antibody (PACO50746)
- SKU:
- PACO50746
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IF
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | TRAPPC11 Antibody (PACO50746) |
| Antibody SKU: | PACO50746 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IF |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IF:1:50-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Trafficking protein particle complex subunit 11 protein (704-836AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Immunofluorescence staining of U251 cells with PACO50746 at 1:100, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).. |
| Background: | Involved in endoplasmic reticulum to Golgi apparatus trafficking at a very early stage. |
| Synonyms: | Trafficking protein particle complex subunit 11, TRAPPC11, C4orf41 |
| UniProt Protein Function: | TRAPPC11: Involved in endoplasmic reticulum to Golgi apparatus trafficking at a very early stage. Belongs to the TRAPPC11 family. 4 isoforms of the human protein are produced by alternative splicing.Protein type: Unknown functionChromosomal Location of Human Ortholog: 4q35.1Cellular Component: Golgi apparatusBiological Process: vesicle-mediated transportDisease: Muscular Dystrophy, Limb-girdle, Type 2s |
| UniProt Protein Details: | |
| NCBI Summary: | The protein encoded by this gene is a subunit of the TRAPP (transport protein particle) tethering complex, which functions in intracellular vesicle trafficking. This subunit is involved in early stage endoplasmic reticulum-to-Golgi vesicle transport. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jan 2013] |
| UniProt Code: | Q7Z392 |
| NCBI GenInfo Identifier: | 39995076 |
| NCBI Gene ID: | 60684 |
| NCBI Accession: | NP_068761.4 |
| UniProt Secondary Accession: | Q7Z392,Q5U5I7, Q6FI73, Q86T25, Q9H0L1, Q9H5K9, Q9H8Q1 Q9H9I7, A4QPB8, B2RCD6 |
| UniProt Related Accession: | Q7Z392 |
| Molecular Weight: | 128,881 Da |
| NCBI Full Name: | trafficking protein particle complex subunit 11 isoform a |
| NCBI Synonym Full Names: | trafficking protein particle complex 11 |
| NCBI Official Symbol: | TRAPPC11 |
| NCBI Official Synonym Symbols: | GRY; FOIGR; LGMD2S; C4orf41 |
| NCBI Protein Information: | trafficking protein particle complex subunit 11; gryzun homolog; foie gras homolog |
| UniProt Protein Name: | Trafficking protein particle complex subunit 11 |
| UniProt Synonym Protein Names: | |
| Protein Family: | |
| UniProt Gene Name: | TRAPPC11 |
| UniProt Entry Name: | TPC11_HUMAN |
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