Transglutaminase 2 (TGM2) Monoclonal Antibody
- SKU:
- CAB21184
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
- Applications:
- IHC
- Applications:
- IF
Description
| Product Name: | Transglutaminase 2 (TGM2) Monoclonal Antibody |
| Product Code: | CAB21184 |
| Reactivity: | Human |
| Applications: | Western blotting, Immunohistochemistry, Immunofluorescence |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC52843 |
| Reactivity: | Human |
| Tested Applications: | WB, IHC-P, IF/ICC, ELISA |
| Key Applications: | Western blotting, Immunohistochemistry, Immunofluorescence |
| Recommended Dilution: | WB 1:2000-1:10000, IHC-P 1:500-1:1000, IF/ICC 1:50-1:200 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
| Positive Samples: | A549, K-562, Hep G2 |
| Cellular Location: | cytosol, endoplasmic reticulum, extracellular exosome, focal adhesion, mitochondrion, nucleus, perinuclear region of cytoplasm, plasma membrane |
Transglutaminases are enzymes that catalyze the crosslinking of proteins by epsilon-gamma glutamyl lysine isopeptide bonds. While the primary structure of transglutaminases is not conserved, they all have the same amino acid sequence at their active sites and their activity is calcium-dependent. The protein encoded by this gene acts as a monomer, is induced by retinoic acid, and appears to be involved in apoptosis. Finally, the encoded protein is the autoantigen implicated in celiac disease. Two transcript variants encoding different isoforms have been found for this gene.
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 438-687 of human Transglutaminase 2 (TGM2) (NP_004604.2). |
| Sequence: | DITHT YKYPE GSSEE REAFT RANHL NKLAE KEETG MAMRI RVGQS MNMGS DFDVF AHITN NTAEE YVCRL LLCAR TVSYN GILGP ECGTK YLLNL NLEPF SEKSV PLCIL YEKYR DCLTE SNLIK VRALL VEPVI NSYLL AERDL YLENP EIKIR ILGEP KQKRK LVAEV SLQNP LPVAL EGCTF TVEGA GLTEE QKTVE IPDPV EAGEE VKVRM DLLPL HMGLH KLVVN FESDK LKAVK GFRNV IIGPA |
| Synonyms: | TGC, tTG, G(h), hTG2, TG(C) |
| Calculated MW: | 77kDa |
| Observed MW: | 77kDa |
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