Description
Antibody Name: | TPTE2 Antibody (PACO37030) |
Antibody SKU: | PACO37030 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, IHC |
Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200 |
Species Reactivity: | Human |
Immunogen: | Recombinant Human Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase TPTE2 protein (167-411AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
Purification Method: | >95%, Protein G purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Immunohistochemistry of paraffin-embedded human liver cancer using PACO37030 at dilution of 1:100. |
Background: | Golgi membrane, phosphatidylinositol biosynthetic process, phospholipid metabolic process, small molecule metabolic process |
Synonyms: | Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase TPTE2 (EC 3.1.3.67) (Lipid phosphatase TPIP) (TPTE and PTEN homologous inositol lipid phosphatase), TPTE2, TPIP |
UniProt Protein Function: | TPTE2: 5 isoforms of the human protein are produced by alternative splicingProtein type: Membrane protein, multi-pass; EC 3.1.3.67; Phosphatase, lipid; Membrane protein, integralChromosomal Location of Human Ortholog: 13q12.11Cellular Component: endoplasmic reticulum membrane; Golgi membrane; integral to membraneMolecular Function: phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity; protein tyrosine phosphatase activity; protein tyrosine/serine/threonine phosphatase activityBiological Process: phosphatidylinositol biosynthetic process; phospholipid metabolic process |
UniProt Protein Details: | |
NCBI Summary: | TPIP is a member of a large class of membrane-associated phosphatases with substrate specificity for the 3-position phosphate of inositol phospholipids.[supplied by OMIM, Jul 2002] |
UniProt Code: | Q6XPS3 |
NCBI GenInfo Identifier: | 213972593 |
NCBI Gene ID: | 93492 |
NCBI Accession: | NP_001135440.1 |
UniProt Secondary Accession: | Q6XPS3,Q5VUH2, Q8WWL4, Q8WWL5, A1A4X0, A1A4X1, A8MX64 B1AQ16, B4DWZ2 |
UniProt Related Accession: | Q6XPS3 |
Molecular Weight: | 56,839 Da |
NCBI Full Name: | phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase TPTE2 isoform delta |
NCBI Synonym Full Names: | transmembrane phosphoinositide 3-phosphatase and tensin homolog 2 |
NCBI Official Symbol: | TPTE2 |
NCBI Official Synonym Symbols: | TPIP |
NCBI Protein Information: | phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase TPTE2 |
UniProt Protein Name: | Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase TPTE2 |
UniProt Synonym Protein Names: | Lipid phosphatase TPIP; TPTE and PTEN homologous inositol lipid phosphatase |
Protein Family: | Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase |
UniProt Gene Name: | TPTE2 |
UniProt Entry Name: | TPTE2_HUMAN |