Tpsb2 Antibody (PACO30747)
- SKU:
- PACO30747
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | Tpsb2 Antibody (PACO30747) |
| Antibody SKU: | PACO30747 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:2000 |
| Species Reactivity: | Mouse, Rat |
| Immunogen: | Recombinant Mouse Tryptase beta-2 protein (32-276AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western blot All lanes: Tpsb2 antibody at 2µg/ml Lane 1: Mouse heart tissue Lane 2: Rat heart tissue Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 31, 26 kDa Observed band size: 31 kDa . |
| Background: | Tryptase is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type. Has an immunoprotective role during bacterial infection. Required to efficiently combat K.pneumoniae infection. |
| Synonyms: | Tryptase beta-2 (Tryptase-2) (EC 3.4.21.59) (Mast cell protease 6) (mMCP-6), Tpsb2, Mcpt6 |
| UniProt Protein Function: | TPSB2: Tryptase is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type. Has an immunoprotective role during bacterial infection. Required to efficiently combat K.pneumoniae infection. Belongs to the peptidase S1 family. Tryptase subfamily. |
| UniProt Protein Details: | Protein type:Secreted, signal peptide; Protease; EC 3.4.21.59; Secreted Cellular Component: extracellular matrix; extracellular region; extracellular space Molecular Function:heparin binding; hydrolase activity; peptidase activity; protein binding; serine-type endopeptidase activity; serine-type peptidase activity Biological Process: inflammatory response; proteolysis |
| UniProt Code: | P21845 |
| NCBI GenInfo Identifier: | 126839 |
| NCBI Gene ID: | 17229 |
| NCBI Accession: | P21845.2 |
| UniProt Secondary Accession: | P21845,Q61962, |
| UniProt Related Accession: | P21845 |
| Molecular Weight: | 25,829 Da |
| NCBI Full Name: | Tryptase beta-2 |
| NCBI Synonym Full Names: | tryptase beta 2 |
| NCBI Official Symbol: | Tpsb2 |
| NCBI Official Synonym Symbols: | Mcp6; Mcp-6; Mcpt6; MMCP-6; AV011504 |
| NCBI Protein Information: | tryptase beta-2 |
| UniProt Protein Name: | Tryptase beta-2 |
| UniProt Synonym Protein Names: | Mast cell protease 6; mMCP-6 |
| Protein Family: | Tryptase |
| UniProt Gene Name: | Tpsb2 |
| UniProt Entry Name: | TRYB2_MOUSE |
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