TPRKB Antibody (PACO42678)
- SKU:
- PACO42678
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | TPRKB Antibody (PACO42678) |
| Antibody SKU: | PACO42678 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:1000-1:5000, IHC:1:20-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human EKC/KEOPS complex subunit TPRKB protein (1-175AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western blot. All lanes: TPRKB antibody at 5µg/ml. Lane 1: A549 whole cell lysate. Lane 2: Jurkat whole cell lysate. Lane 3: MCF-7 whole cell lysate. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 20, 17, 24 kDa. Observed band size: 20 kDa. |
 | Immunohistochemistry of paraffin-embedded human adrenal gland tissue using PACO42678 at dilution of 1:100. |
 | Immunohistochemistry of paraffin-embedded human lung tissue using PACO42678 at dilution of 1:100. |
| Background: | Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. TPRKB acts as an allosteric effector that regulates the t(6)A activity of the complex. TPRKB is not required for tRNA modification. |
| Synonyms: | EKC/KEOPS complex subunit TPRKB (PRPK-binding protein) (TP53RK-binding protein), TPRKB |
| UniProt Protein Function: | TPRKB: Belongs to the CGI121/TPRKB family. 3 isoforms of the human protein are produced by alternative splicing.Chromosomal Location of Human Ortholog: 2p24.3-p24.1Cellular Component: cytoplasm; cytosol; nucleusMolecular Function: protein binding; protein kinase bindingBiological Process: tRNA processing |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q9Y3C4 |
| NCBI GenInfo Identifier: | 7705590 |
| NCBI Gene ID: | 51002 |
| NCBI Accession: | NP_057142.1 |
| UniProt Secondary Accession: | Q9Y3C4,Q8IWR6, Q8IWR7, Q9H3K4, D6W5H6 |
| UniProt Related Accession: | Q9Y3C4 |
| Molecular Weight: | 19,661 Da |
| NCBI Full Name: | EKC/KEOPS complex subunit TPRKB |
| NCBI Synonym Full Names: | TP53RK binding protein |
| NCBI Official Symbol: | TPRKB |
| NCBI Official Synonym Symbols: | CGI-121 |
| NCBI Protein Information: | EKC/KEOPS complex subunit TPRKB; PRPK-binding protein; TP53RK-binding protein; PRPK (p53-related protein kinase)-binding protein |
| UniProt Protein Name: | EKC/KEOPS complex subunit TPRKB |
| UniProt Synonym Protein Names: | PRPK-binding protein; TP53RK-binding protein |
| Protein Family: | EKC/KEOPS complex |
| UniProt Gene Name: | TPRKB |
| UniProt Entry Name: | TPRKB_HUMAN |
| Antibodies |
| TPRKB Antibody (PACO12873) |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
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