Tpbg Antibody (PACO30730)
- SKU:
- PACO30730
- Product Type:
- Antibody
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | Tpbg Antibody (PACO30730) |
| Antibody SKU: | PACO30730 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA |
| Recommended Dilutions: | |
| Species Reactivity: | Rat |
| Immunogen: | Recombinant Rat Trophoblast glycoprotein protein (32-361AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Background: | May function as an inhibitor of Wnt/beta-catenin signaling by indirectly interacting with LRP6 and blocking Wnt3a-dependent LRP6 internalization. |
| Synonyms: | Trophoblast glycoprotein (5T4 oncofetal trophoblast glycoprotein) (5T4 oncotrophoblast glycoprotein) (Wnt-activated inhibitory factor 1) (WAIF1), Tpbg, 5t4 |
| UniProt Protein Function: | Subcellular location: Membrane; Single-pass type I membrane protein Potential. Tissue specificity: Expressed by all types of trophoblasts as early as 9 weeks of development. Specific for trophoblastic cells except for amniotic epithelium. In adult tissues, the expression is limited to a few epithelial cell types but is found on a variety of carcinoma.Miscellaneous: Antigen 5T4 is overexpressed by a wide spectrum of cancers, including colorectal, ovarian and gastric, but with a limited normal tissue expression. Could be used for tumor immunotherapy.Sequence similarities: Contains 6 LRR (leucine-rich) repeats.Contains 1 LRRCT domain.Contains 1 LRRNT domain. |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q5PQV5 |
| NCBI GenInfo Identifier: | 262205665 |
| NCBI Gene ID: | |
| NCBI Accession: | NP_001159864.1 |
| UniProt Secondary Accession: | Q5PQV5,Q9Z0L0, Q5PQV5 |
| UniProt Related Accession: | Q5PQV5 |
| Molecular Weight: | 72kDa |
| NCBI Full Name: | trophoblast glycoprotein |
| NCBI Synonym Full Names: | |
| NCBI Official Symbol: | |
| NCBI Official Synonym Symbols: | |
| NCBI Protein Information: | |
| UniProt Protein Name: | Trophoblast glycoprotein |
| UniProt Synonym Protein Names: | 5T4 oncofetal antigen; 5T4 oncofetal trophoblast glycoprotein; 5T4 oncotrophoblast glycoprotein; M6P1 |
| Protein Family: | |
| UniProt Gene Name: | TPBG |
| UniProt Entry Name: | TPBG_HUMAN |
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