TP53INP2 Antibody (PACO46778)
- SKU:
- PACO46778
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IF
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | TP53INP2 Antibody (PACO46778) |
| Antibody SKU: | PACO46778 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IF |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IF:1:50-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Tumor protein p53-inducible nuclear protein 2 protein (100-220AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Immunofluorescent analysis of MCF-7 cells using PACO46778 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
| Background: | Dual regulator of transcription and autophagy. Positively regulates autophagy and is required for autophagosome formation and processing. May act as a scaffold protein that recruits MAP1LC3A, GABARAP and GABARAPL2 and brings them to the autophagosome membrane by interacting with VMP1 where, in cooperation with the BECN1-PI3-kinase class III complex, they trigger autophagosome development. Acts as a transcriptional activator of THRA. |
| Synonyms: | Tumor protein p53-inducible nuclear protein 2 (Diabetes and obesity-regulated gene) (p53-inducible protein U) (PIG-U), TP53INP2, C20orf110 DOR PINH |
| UniProt Protein Function: | TP53INP2: Dual regulator of transcription and autophagy. Positively regulates autophagy and is required for autophagosome formation and processing. May act as a scaffold protein that recruits MAP1LC3A, GABARAP and GABARAPL2 and brings them to the autophagosome membrane by interacting with VMP1 where, in cooperation with the BECN1-PI3-kinase class III complex, they trigger autophagosome development. Acts as a transcriptional activator of THRA.Chromosomal Location of Human Ortholog: 20q11.22Cellular Component: autophagic vacuole; cytoplasmic vesicle; cytosol; nucleus; PML bodyMolecular Function: protein binding; ubiquitin bindingBiological Process: autophagic vacuole formation; osteoblast differentiation; positive regulation of autophagy; positive regulation of transcription, DNA-dependent; tissue homeostasis; transcription, DNA-dependent; ubiquitin-dependent protein catabolic process |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q8IXH6 |
| NCBI GenInfo Identifier: | 32699566 |
| NCBI Gene ID: | 58476 |
| NCBI Accession: | Q8IXH6.2 |
| UniProt Secondary Accession: | Q8IXH6,Q5JX64, Q8IYL5, Q9NU00, A8K8S8, E1P5P6 |
| UniProt Related Accession: | Q8IXH6 |
| Molecular Weight: | 23,980 Da |
| NCBI Full Name: | Tumor protein p53-inducible nuclear protein 2 |
| NCBI Synonym Full Names: | tumor protein p53 inducible nuclear protein 2 |
| NCBI Official Symbol: | TP53INP2 |
| NCBI Official Synonym Symbols: | DOR; PINH; C20orf110; dJ1181N3.1 |
| NCBI Protein Information: | tumor protein p53-inducible nuclear protein 2 |
| UniProt Protein Name: | Tumor protein p53-inducible nuclear protein 2 |
| UniProt Synonym Protein Names: | Diabetes and obesity-regulated gene; p53-inducible protein U; PIG-U |
| Protein Family: | Tumor protein p53-inducible nuclear protein |
| UniProt Gene Name: | TP53INP2 |
| UniProt Entry Name: | T53I2_HUMAN |
| Antibodies |
| TP53INP2 Antibody (PACO04856) |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
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