TP53INP2 Antibody (PACO04856)
- SKU:
- PACO04856
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Applications:
- IF
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | TP53INP2 Antibody |
| Antibody SKU: | PACO04856 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC, IF |
| Recommended Dilutions: | IHC:1:100-1:300, IF:1:200-1:1000 |
| Species Reactivity: | Human, Mouse, Rat |
| Immunogen: | synthesized peptide derived from the N-terminal region of human TP53INP2. |
| Form: | Liquid |
| Storage Buffer: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Synonyms: | TP53INP2; C20orf110; DOR; PINH; Tumor protein p53-inducible nuclear protein 2; Diabetes and obesity-regulated gene; p53-inducible protein U; PIG-U |
| UniProt Protein Function: | TP53INP2: Dual regulator of transcription and autophagy. Positively regulates autophagy and is required for autophagosome formation and processing. May act as a scaffold protein that recruits MAP1LC3A, GABARAP and GABARAPL2 and brings them to the autophagosome membrane by interacting with VMP1 where, in cooperation with the BECN1-PI3-kinase class III complex, they trigger autophagosome development. Acts as a transcriptional activator of THRA.Chromosomal Location of Human Ortholog: 20q11.22Cellular Component: autophagic vacuole; cytoplasmic vesicle; cytosol; nucleus; PML bodyMolecular Function: protein binding; ubiquitin bindingBiological Process: autophagic vacuole formation; osteoblast differentiation; positive regulation of autophagy; positive regulation of transcription, DNA-dependent; tissue homeostasis; transcription, DNA-dependent; ubiquitin-dependent protein catabolic process |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q8IXH6 |
| NCBI GenInfo Identifier: | 32699566 |
| NCBI Gene ID: | 58476 |
| NCBI Accession: | Q8IXH6.2 |
| UniProt Secondary Accession: | Q8IXH6,Q5JX64, Q8IYL5, Q9NU00, A8K8S8, E1P5P6 |
| UniProt Related Accession: | Q8IXH6 |
| Molecular Weight: | 23,980 Da |
| NCBI Full Name: | Tumor protein p53-inducible nuclear protein 2 |
| NCBI Synonym Full Names: | tumor protein p53 inducible nuclear protein 2 |
| NCBI Official Symbol: | TP53INP2 |
| NCBI Official Synonym Symbols: | DOR; PINH; C20orf110; dJ1181N3.1 |
| NCBI Protein Information: | tumor protein p53-inducible nuclear protein 2 |
| UniProt Protein Name: | Tumor protein p53-inducible nuclear protein 2 |
| UniProt Synonym Protein Names: | Diabetes and obesity-regulated gene; p53-inducible protein U; PIG-U |
| Protein Family: | Tumor protein p53-inducible nuclear protein |
| UniProt Gene Name: | TP53INP2 |
| UniProt Entry Name: | T53I2_HUMAN |
Related Products
SIM1 Antibody
Overview Product Name:SIM1 AntibodyProduct Code:PACO64949Size:50µLTarget Names:SIM1Species Reactivity:HumanHost
eutC Antibody
Overview Product Name:eutC AntibodyProduct Code:PACO64709Size:50µLTarget Names:eutCSpecies Reactivity:Escherichia coli
EPHA10 Antibody
Overview Product Name:EPHA10 AntibodyProduct Code:PACO64693Size:50µLTarget Names:EPHA10Species Reactivity:HumanH