Description
system_update_alt Datasheet
| Product Name: | TP53I3 Antibody |
| Product Sku: | CPAB0117 |
| Size: | 5μg |
| Host Species: | Mouse |
| Immunogen: | Anti-human TP53I3 mAb, is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human TP53I3 amino acids 1-332 purified from Ecoli. |
| Clone: | P1C9AT. |
| Reactivity: | Human |
| Applications: | Western Blot, ELISA |
| Purification Method: | TP53I3 antibody was purified from mouse ascitic fluids by protein-G affinity chromatography. |
| Isotype: | IgG2a |
| Background: | TP53I3 participates in the generation of reactive oxygen species (ROS). TP53I3 has low NADPH-dependent naphtoquinone reductase activity, with a preference for 1,2-naphtoquinone over 1,4-naphtoquinone. TP53I3 has low NADPH-dependent diamine reductase activity (in vitro). TP53I3 is localized to the cytoplasm and induced in primary, non-transformed and transformed cell cultures after exposure to genotoxic agents. TP53I3 microsatellite polymorphism is associated with differential susceptibility to cancer. |
| Synonyms: | TP53I3, PIG3, Quinone Oxidoreductase, tumor protein p53 inducible protein 3. |
| Storage Buffer: | For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles. |