Description
Product Name: | TP53BP2 Polyclonal Antibody |
Product Code: | CAB21633 |
Reactivity: | Human |
Applications: | Western blotting |
Host Species: | Rabbit |
Purification Method: | Affinity purification |
Isotype: | IgG |
Reactivity: | Human |
Tested Applications: | WB, ELISA |
Key Applications: | Western blotting |
Recommended Dilution: | WB 1:500-1:2000 |
Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal, 50% glycerol, pH7.3. |
Cellular Location: | Cytoplasm, Nucleus, perinuclear region |
This gene encodes a member of the ASPP (apoptosis-stimulating protein of p53) family of p53 interacting proteins. The protein contains four ankyrin repeats and an SH3 domain involved in protein-protein interactions. It is localized to the perinuclear region of the cytoplasm, and regulates apoptosis and cell growth through interactions with other regulatory molecules including members of the p53 family. Multiple transcript variants encoding different isoforms have been found for this gene.
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 200-330 of TP53BP2 (NP_001026855.2). |
Sequence: | RALKG HVEQK RLSNG KLVEE IEQMN NLFQQ KQREL VLAVS KVEEL TRQLE MLKNG RIDSH HDNQS AVAEL DRLYK ELQLR NKLNQ EQNAK LQQQR ECLNK RNSEV AVMDK RVNEL RDRLW KKKAA LQQKE N |
Synonyms: | BBP, 53BP2, ASPP2, P53BP2, PPP1R13A |
Calculated MW: | 126kDa |
Observed MW: | Refer to figures |