Antibody Name:	Toxin zeta Antibody (PACO34894)
Antibody SKU:	PACO34894
Size:	50ug
Host Species:	Rabbit
Tested Applications:	ELISA
Recommended Dilutions:
Species Reactivity:	Streptococcus agalactiae
Immunogen:	Recombinant Streptococcus agalactiae Toxin zeta protein (1-287AA)

Form:	Liquid
Storage Buffer:	Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Purification Method:	>95%, Protein G purified
Clonality:	Polyclonal
Isotype:	IgG
Conjugate:	Non-conjugated

Background:

Toxic component of a toxin-antitoxin (TA) module. Phosphorylates UDP-N-acetyl-D-glucosamine (UNAG) on the 3'-hydroxyl group of the N-acetyl-D-glucosamine moiety, yielding UNAG-3P. UNAG-3P inhibits MurA, the first committed step in cell wall synthesis, which is then blocked. Phosphorylation is inhibited by cognate epsilon antitoxin. Part of a postsegregational killing (PSK) system involved in the killing of plasmid-free cells. The zeta toxin induces programmed cell death

Synonyms:

Toxin zeta (UDP-N-acetylglucosamine kinase) (UNAG kinase) (EC 2.7.1.176)

UniProt Protein Function:	Toxic component of a toxin-antitoxin (TA) module. Phosphorylates UDP-N-acetyl-D-glucosamine (UNAG) on the 3'-hydroxyl group of the N-acetyl-D-glucosamine moiety, yielding UNAG-3P. UNAG-3P inhibits MurA, the first committed step in cell wall synthesis, which is then blocked. Phosphorylation is inhibited by cognate epsilon antitoxin. Part of a postsegregational killing (PSK) system involved in the killing of plasmid-free cells. The zeta toxin induces programmed cell death ().
UniProt Protein Details:
NCBI Summary:
UniProt Code:	P0A4M2
NCBI GenInfo Identifier:	61252185
NCBI Gene ID:
NCBI Accession:
UniProt Secondary Accession:	P0A4M2,Q9AL18
UniProt Related Accession:	P0A4M2
Molecular Weight:	34.7kD
NCBI Full Name:	Toxin zeta
NCBI Synonym Full Names:
NCBI Official Symbol:
NCBI Official Synonym Symbols:
NCBI Protein Information:
UniProt Protein Name:	Toxin zeta
UniProt Synonym Protein Names:	UDP-N-acetylglucosamine kinase (EC:2.7.1.176); UNAG kinase
Protein Family:	Toxin
UniProt Gene Name:	UNAG kinase
UniProt Entry Name: