TNNI3 Paired Monoclonal Antibody (CPAB0658)

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SKU:
CPAB0658
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Universal

Description

system_update_alt Datasheet
Product Name:TNNI3 Paired Antibody
Product Sku:CPAB0658
Size:100μg
Host Species:
Immunogen:
Clone:
Reactivity:Other bodies
Applications:
Purification Method:Purified monoclonal IgG by protein A chromatography.
Isotype:
Background:Troponin I (TnI), troponin T (TnT) and troponin C (TnC) form the troponin complex of the thin filaments of striated muscle. TnI is acts as the inhibitory subunit by blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains 3 genes: TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. The TNNI3 gene encodes the TnI-cardiac protein and is exclusively expressed in cardiac muscle tissues. Mutations in the TNNI3 gene cause familial hypertrophic cardiomyopathy type 7 (CMH7) and familial restrictive cardiomyopathy (RCM).
Synonyms:Troponin I cardiac muscle, Cardiac troponin I, TNNI3, TNNC1, CMH7, RCM1, cTnI, CMD2A, MGC116817.
Storage Buffer:
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