Description
Antibody Name: | Tnni3 Antibody (PACO52194) |
Antibody SKU: | PACO52194 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB |
Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:5000 |
Species Reactivity: | Mouse, Rat |
Immunogen: | Recombinant Mouse Troponin I, cardiac muscle protein (2-211AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
Purification Method: | >95%, Protein G purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Western Blot. Positive WB detected in: Rat heart tissue, Rat liver tissue. All lanes: Tnni3 antibody at 2.5µg/ml. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 25 kDa. Observed band size: 25 kDa. |
Background: | Troponin I is the inhibitory subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity. |
Synonyms: | Troponin I, cardiac muscle (Cardiac troponin I), Tnni3 |
UniProt Protein Function: | TNNI3: Troponin I is the inhibitory subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity. Binds to actin and tropomyosin. Interacts with TRIM63. Interacts with STK4/MST1. Belongs to the troponin I family. |
UniProt Protein Details: | Protein type:Actin-binding; Motor; Motility/polarity/chemotaxis Cellular Component: contractile fiber; cytoplasm; myofibril; sarcomere; troponin complex Molecular Function:actin binding; calcium channel inhibitor activity; calcium-dependent protein binding; metal ion binding; protein domain specific binding; protein kinase binding; troponin C binding; troponin T binding Biological Process: cardiac muscle contraction; cellular calcium ion homeostasis; heart contraction; heart development; negative regulation of ATPase activity; regulation of muscle contraction; regulation of smooth muscle contraction; regulation of systemic arterial blood pressure by ischemic conditions; skeletal muscle contraction; striated muscle contraction; vasculogenesis; ventricular cardiac muscle morphogenesis |
UniProt Code: | P48787 |
NCBI GenInfo Identifier: | 6678393 |
NCBI Gene ID: | 21954 |
NCBI Accession: | NP_033432.1 |
UniProt Related Accession: | P48787 |
Molecular Weight: | |
NCBI Full Name: | troponin I, cardiac muscle |
NCBI Synonym Full Names: | troponin I, cardiac 3 |
NCBI Official Symbol: | Tnni3 |
NCBI Official Synonym Symbols: | Tn1; cTnI |
NCBI Protein Information: | troponin I, cardiac muscle |
UniProt Protein Name: | Troponin I, cardiac muscle |
UniProt Synonym Protein Names: | Cardiac troponin I |
UniProt Gene Name: | Tnni3 |
UniProt Entry Name: | TNNI3_MOUSE |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |